| Gene Symbol | HOMER3 |
|---|---|
| Entrez Gene | 9454 |
| Alt Symbol | HOMER-3, VESL3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | homer scaffolding protein 3 |
| Other Description | Homer, neuronal immediate early gene, 3|homer homolog 3|homer protein homolog 3 |
| Swissprots | E9PCW9 O95350 Q9NSB9 Q9NSC5 Q9NSC1 Q9NSC0 O14580 |
| Accessions | AAB81545 EAW84762 EAW84763 EAW84764 EAW84765 Q9NSC5 AF093265 AAC71029 AK124450 BAG54040 AK313995 BAG36707 AL529052 AW606967 BC012113 AAH12113 BM915739 BT019464 AAV38271 CN284196 DQ892557 ABM83483 DQ895771 ABM86697 Y17573 CAB75536 Y18894 CAB75543 Y18895 CAB75544 Y18896 CAB75545 XM_006722943 XP_006723006 XM_006722944 XP_006723007 NM_001145721 NP_001139193 NM_001145722 NP_001139194 NM_001145724 NP_001139196 NM_004838 NP_004829 NR_027297 |
| Function | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Postsynaptic density of neuronal cells. {ECO:0000250}. |
| Top Pathways | Glutamatergic synapse |
ANKRD60 siRNA (h) - sc-72747 from Santa Cruz Biotechnology
|
||||||||
ANKRD60 shRNA Plasmid (h) - sc-72747-SH from Santa Cruz Biotechnology
|
||||||||
ANKRD60 shRNA (h) Lentiviral Particles - sc-72747-V from Santa Cruz Biotechnology
|
||||||||
Homer-3 CRISPR/Cas9 KO Plasmid (h) - sc-401976 from Santa Cruz Biotechnology
|
||||||||
Homer-3 HDR Plasmid (h) - sc-401976-HDR from Santa Cruz Biotechnology
|
||||||||
Homer-3 Double Nickase Plasmid (h) - sc-401976-NIC from Santa Cruz Biotechnology
|
||||||||
Homer-3 Double Nickase Plasmid (h2) - sc-401976-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Homer-3 CRISPR Activation Plasmid (h) - sc-401976-ACT from Santa Cruz Biotechnology
|
||||||||
Homer-3 CRISPR Activation Plasmid (h2) - sc-401976-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Homer-3 Lentiviral Activation Particles (h) - sc-401976-LAC from Santa Cruz Biotechnology
|
||||||||
Homer-3 Lentiviral Activation Particles (h2) - sc-401976-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Homer-3 siRNA (h) - sc-43850 from Santa Cruz Biotechnology
|
||||||||
Homer-3 shRNA Plasmid (h) - sc-43850-SH from Santa Cruz Biotechnology
|
||||||||
Homer-3 shRNA (h) Lentiviral Particles - sc-43850-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10219 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10219 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR01674 from Sigma-Aldrich
|
||||||||
HOMER3 siRNA (Human) - CRH6272 from Cohesion Biosciences
|
||||||||
HOMER3 - MBS8231713 from MyBioSource
|
||||||||
shRNA set against Human HOMER3 (NM_004838.3) - SHH313973 from Creative biogene
|
||||||||
Human HOMER3 siRNA - orb266774 from Biorbyt
|
||||||||
HOMER3 shRNA Plasmid (Human) - CHH6272 from Cohesion Biosciences
|
||||||||
HOMER3 miRNA 3'UTR clone - MiUTR3H-07095 from Creative biogene
|
||||||||
HOMER3 miRNA 3'UTR clone - MiUTR3H-07096 from Creative biogene
|
||||||||
HOMER3 miRNA 3'UTR clone - MiUTR3H-07097 from Creative biogene
|