ELP3

Gene Symbol ELP3
Entrez Gene 55140
Alt Symbol KAT9
Species Human
Gene Type protein-coding
Description elongator acetyltransferase complex subunit 3
Other Description elongation protein 3 homolog|elongator complex protein 3
Swissprots E2QRI5 Q9H9T3 Q6AWB0 Q53G84 Q9BVF7 B4DIG1 B4DE19 Q9NVZ1
Accessions EAW63528 EAW63529 Q9H9T3 AK001284 BAA91600 AK022626 BAB14138 AK223047 BAD96767 AK293424 BAG56930 AK295574 BAG58473 AK296475 BAG59116 AK298265 BAG60529 AK302140 BAG63513 AK315985 BAH14356 AK316053 BAH14424 AL834273 CAD38948 AM392633 CAL37511 BC001240 AAH01240 BM663362 BU683531 BX648011 CAH10573 DA150994 DA787116 DA877844 XM_006716354 XP_006716417 NM_001284220 NP_001271149 NM_001284222 NP_001271151 NM_001284224 NP_001271153 NM_001284225 NP_001271154 NM_001284226 NP_001271155 NM_018091 NP_060561
Function Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin (PubMed:19185337). May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha- tubulin acetylation (By similarity). {ECO:0000250|UniProtKB:Q9CZX0, ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:15902492, ECO:0000269|PubMed:16713582, ECO:0000269|PubMed:19185337}.
Subcellular Location Isoform 2: Cytoplasm. Nucleus.
Tissue Specificity Expressed in the cerebellum and spinal motor neurons. {ECO:0000269|PubMed:18996918}.

ELP3 (D5H12) Rabbit mAb - 5728 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5H12
Western blot analysis of extracts from various cell lines using ELP3 (D5H12) Rabbit mAb.

ELP3 (C-18) - sc-323807 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ELP3 (K-19) - sc-323806 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KAT9 / Elp3 antibody - ab113228 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab113228, at 10µg/ml, staining KAT9 / Elp3 in Formalin-fixed, Paraffin-embedded Human Tonsil tissue by Immunohistochemistry.

Anti-KAT9 / Elp3 antibody - ab96781 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-KAT9 / Elp3 antibody (ab96781) at 1/2000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-KAT9 / Elp3 antibody - ab55923 from Abcam

Prices $373.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KAT9 / Elp3 antibody - ab89718 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-KAT9 / Elp3 antibody (ab89718) at 1 µg/ml + K562 cell lysate at 50 µg

Anti-KAT9 / Elp3 antibody - C-terminal - ab71270 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KAT9 / Elp3 antibody - C-terminal (ab71270) at 1/50 dilutionLane 1 : Non-transfected 293 cell lysateLane 2 : 293 cell lysate transiently transfected with the KAT9 / Elp3 geneLysates/proteins at 2 µg per lane.

Anti-KAT9 / Elp3 antibody - N-terminal - ab167437 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KAT9 / Elp3 antibody - N-terminal (ab167437) at 1 µg/ml + Rat thymus lysate at 10 µgSecondaryGoat anti-rabbit IgG HRP

Anti-ELP3 Antibody (C-Terminus) - LS-C46984 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELP3 Antibody - LS-C310246 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELP3 Antibody - LS-C307390 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ELP3 Antibody (aa468-498) - LS-C98653 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with ELP3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-ELP3 Antibody (aa9-44) - LS-C98652 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ELP3 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The ELP3 antibody detected the ELP3 protein (arrow).

Anti-ELP3 Antibody IHC-plus™ - LS-B4860 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-ELP3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4860 concentration 10 ug/ml.

Elp3 Antibody - NBP1-84625 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Elp3 Antibody [NBP1-84625] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-183

Elp3 Antibody - H00055140-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Elp3 Antibody [H00055140-B01P] - Analysis of ELP3 expression in K-562.

Anti-ELP3 (N-term) antibody produced in rabbit - SAB1300520 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ELP3 (N-term) Antibody: <B>Cat. No. SAB1300520</B>: ELP3 in HEK 293 cell line lysates either non-transfected (Lane 1) or transiently transfected (Lane 2) with Anti-ELP3 (N-term) Antibody at 4.0 μg/mL.

Anti-ELP3 antibody produced in mouse - SAB1407619 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ELP3: <B>Cat. No. SAB1407619</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~62.3 kDa using K~562 lysate.

Anti-ELP3 antibody produced in rabbit - SAB1401743 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-ELP3, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401743</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~62.26 kDa using A-431 lysate.

Anti-ELP3 antibody produced in rabbit - HPA025812 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ELP3: <B>Cat. No. HPA025812</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells.

Anti-ELP3 (C-term) antibody produced in rabbit - SAB1300151 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ELP3 (C-term) Antibody: <B>Cat. No. SAB1300151</B>: ELP3 in human testis tissue with Anti-ELP3 (C-term) Antibody at 40 μg/mL.

ELP3 Antibody - C-terminal region (OAAB01104) - OAAB01104 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ELP3-Antibody-C-term - AP1112b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ELP3 (arrow) using rabbit polyclonal ELP3 Antibody (C-term) (Cat.#AP1112b).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ELP3 gene (Lane 2) (Origene Technologies).

ELP3-Antibody-N-term - AP1112a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ELP3(arrow) using rabbit polyclonal ELP3 Antibody (N-term) (Cat.#AP1112a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ELP3 gene (Lane 2) (Origene Technologies).
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