Gene Symbol | ELP3 |
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Entrez Gene | 55140 |
Alt Symbol | KAT9 |
Species | Human |
Gene Type | protein-coding |
Description | elongator acetyltransferase complex subunit 3 |
Other Description | elongation protein 3 homolog|elongator complex protein 3 |
Swissprots | E2QRI5 Q9H9T3 Q6AWB0 Q53G84 Q9BVF7 B4DIG1 B4DE19 Q9NVZ1 |
Accessions | EAW63528 EAW63529 Q9H9T3 AK001284 BAA91600 AK022626 BAB14138 AK223047 BAD96767 AK293424 BAG56930 AK295574 BAG58473 AK296475 BAG59116 AK298265 BAG60529 AK302140 BAG63513 AK315985 BAH14356 AK316053 BAH14424 AL834273 CAD38948 AM392633 CAL37511 BC001240 AAH01240 BM663362 BU683531 BX648011 CAH10573 DA150994 DA787116 DA877844 XM_006716354 XP_006716417 NM_001284220 NP_001271149 NM_001284222 NP_001271151 NM_001284224 NP_001271153 NM_001284225 NP_001271154 NM_001284226 NP_001271155 NM_018091 NP_060561 |
Function | Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin (PubMed:19185337). May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha- tubulin acetylation (By similarity). {ECO:0000250|UniProtKB:Q9CZX0, ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:15902492, ECO:0000269|PubMed:16713582, ECO:0000269|PubMed:19185337}. |
Subcellular Location | Isoform 2: Cytoplasm. Nucleus. |
Tissue Specificity | Expressed in the cerebellum and spinal motor neurons. {ECO:0000269|PubMed:18996918}. |
Human KAT9 / Elp3 full length protein - ab105858 from Abcam
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Human KAT9 / Elp3 full length protein - ab153393 from Abcam
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KAT9 / Elp3 peptide - ab173823 from Abcam
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ELP3 Antibody Blocking Peptide - LS-E776 from LifeSpan Bioscience
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ELP3 Antibody Blocking Peptide - LS-E777 from LifeSpan Bioscience
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Recombinant Human Elp3 Protein - H00055140-P01 from Novus Biologicals
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Elp3 Peptide - P0230 from Novus Biologicals
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Elp3 Peptide - P0231 from Novus Biologicals
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ELP3-Antibody-C-term-Blocking-Peptide - BP1112b from Abgent, a WuXi AppTec company
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ELP3-Antibody-N-term-Blocking-Peptide - BP1112a from Abgent, a WuXi AppTec company
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ELP3 - H00055140-P01 from Acris Antibodies
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ELP3 fusion protein - ag9993 from Proteintech Group
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Recombinant Human Elongation Protein 3 Homolog (S. Cerevisiae), GST-tagged - ELP3-1583H from Creative Biomart
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Recombinant Human ELP3 - ELP3-28681TH from Creative Biomart
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Recombinant Human ELP3, GST-tagged - ELP3-12424H from Creative Biomart
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KAT9 (ELP3)-GST fusion - 009-001-S30 from Rockland Immunochemicals Inc
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KAT9 (ELP3)-GST fusion - 009-001-S30S from Rockland Immunochemicals Inc
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Recombinant Human Elongator complex protein 3(ELP3) - CSB-YP884499HU CSB-EP884499HU CSB-BP884499HU CSB-MP884499HU from Cusabio
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Elp3 Recombinant Protein Antigen - NBP1-84625PEP from Novus Biologicals
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ELP3 Peptide, Human - M34GP04883H from Creative Peptides
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Elongator complex protein 3 (ELP3), Recombinant Protein - MBS1343686 from MyBioSource
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KAT9 (ELP3), Recombinant Protein - MBS515148 from MyBioSource
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