GALNT11

Gene Symbol GALNT11
Entrez Gene 63917
Alt Symbol GALNAC-T11, GALNACT11
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 11
Other Description UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)|polypeptide GalNAc transferase 11|pp-GaNTase 11|protein-UDP acetylgalactosaminyltransferase 11
Swissprots Q9H6Z5 Q9UDR8 Q8NCW6 Q9H6C2 B3KWF4 Q6PCD1
Accessions AAD45821 CAD38481 CCQ43678 EAL24518 EAW53975 EAW53976 Q8NCW6 AK025287 BAB15105 AK026056 BAB15338 AK124934 BAG54116 AK128545 AK296097 BAH12255 AK298911 BAH12901 BC059377 AAH59377 BC167834 AAI67834 BE349504 BM998376 CN309655 DA308896 DA679635 DA748534 Y12434 CAC79625 XM_006716082 XP_006716145 XM_006716083 XP_006716146 XM_006716084 XP_006716147 NM_001304514 NP_001291443 NM_022087 NP_071370
Function Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N- acetylgalactosaminyltransferases catalyze the transfer of an N- acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO). {ECO:0000269|PubMed:11925450, ECO:0000269|PubMed:24226769}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:11925450}; Single-pass type II membrane protein {ECO:0000269|PubMed:11925450}.
Tissue Specificity Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli. {ECO:0000269|PubMed:11925450}.
Top Pathways Mucin type O-Glycan biosynthesis

GALNT11 Antibody Blocking Peptide - LS-E5495 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GALNT11 Antibody Blocking Peptide - LS-E17933 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GALNT11 Protein - H00063917-G01-10ug from Novus Biologicals

Category Protein
Prices $569.00
Sizes 10 µg
Species Human

GLT11-Antibody-N-term-Blocking-Peptide - BP18017a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Galnt11 Blocking Peptide - 33R-4989 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GALNT11 fusion protein - ag11495 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

GALNT11 fusion protein - ag11684 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 11(GALNT11) - CSB-YP847687HU CSB-EP847687HU CSB-BP847687HU CSB-MP847687HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human GALNT11 Protein, CF - 8905-GT from R&D Systems

Category Protein
Prices $359.00
Sizes 20 µg
Source Chinese Hamster Ovary cell line, CHO-derived Phe30-Gly608, with C-terminal 6-His tag
Species Human

Polypeptide N-acetylgalactosaminyltransferase 11 (GALNT11), Recombinant Protein - MBS1435063 from MyBioSource

Category Protein
Prices $1,400.00, $1,400.00, $1,630.00, $1,630.00, $2,360.00, $2,360.00, $2,805.00, $2,805.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

GALNT11 Recombinant Protein Antigen - NBP1-82140PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

GALNT11 Peptide, Human - M34GP06076H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human GALNT11 Protein, CF - 8905-GT from Novus Biologicals

Category Protein
Prices $359.00
Sizes 20 µg
Species Human

Recombinant Human GALNT11 Protein, His-tagged - GALNT11-001H from Creative Biomart

Category Protein
Source CHO
Species Human
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