BBS7

Gene Symbol BBS7
Entrez Gene 55212
Alt Symbol BBS2L1
Species Human
Gene Type protein-coding
Description Bardet-Biedl syndrome 7
Other Description BBS2-like 1|Bardet-Biedl syndrome 7 protein
Swissprots Q8N581 Q8IWZ6 Q9NVI4 Q4W5P8
Accessions AAY40970 EAX05244 EAX05245 Q8IWZ6 AF521643 AAO16025 AF521644 AAO16026 AI220177 AK001577 BAA91767 AK308076 AK309803 BC032691 AAH32691 BF431967 BG720664 BM998707 BQ940332 BX510161 DB139794 DQ890888 ABM81814 DQ896810 ABM87809 XM_005263106 XP_005263163 XM_011532079 XP_011530381 XM_011532080 XP_011530382 XM_011532081 XP_011530383 NM_018190 NP_060660 NM_176824 NP_789794
Function The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. {ECO:0000269|PubMed:17574030, ECO:0000269|PubMed:22072986}.
Subcellular Location Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Tissue Specificity Isoform 2 is ubiquitously expressed. Isoform 1 is expressed in retina, lung, liver, testis, ovary, prostate, small intestine, liver, brain, heart and pancreas.

BBS7 (E-8) - sc-390403 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BBS7 (E-8): sc-390403. Western blot analysis of BBS7 expression in non-transfected: sc-117752 (A) and mouse BBS7 transfected: sc-118689 (B) 293T whole cell lysates.

BBS7 (C-16) - sc-49802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS7 (C-16): sc-49802. Western blot analysis of BBS7 expression in non-transfected: sc-117752 (A) and human BBS7 transfected: sc-115165 (B) 293T whole cell lysates.

BBS7 (D-20) - sc-49803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS7 (D-20): sc-49803. Western blot analysis of BBS7 expression in A431 whole cell lysate (A) and mouse heart tissue extract (B).

BBS7 (L-19) - sc-49804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS7 (L-19): sc-49804. Western blot analysis of BBS7 expression in non-transfected: sc-117752 (A) and mouse BBS7 transfected: sc-118689 (B) 293T whole cell lysates.

BBS7 (H-300) - sc-99094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BBS7 (H-300): sc-99094. Western blot analysis of BBS7 expression in non-transfected: sc-117752 (A) and mouse BBS7 transfected: sc-118689 (B) 293T whole cell lysates.

Anti-BBS7 antibody - ab96332 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-BBS7 antibody (ab96332) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-BBS7 antibody - ab172790 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-BBS7 antibody (ab172790) at 1 µg/mlLane 1 : BBS7 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-BBS7 antibody - ab55023 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55023 BBS7 antibody at 1ug/ml.

Anti-BBS7 antibody - N-terminal - ab173221 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BBS7 antibody - N-terminal (ab173221) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

Anti-BBS7 Antibody (aa73-99, APC) - LS-C233074 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa73-99, FITC) - LS-C233076 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa73-99, Biotin) - LS-C233075 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa73-99, PE) - LS-C233077 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa73-99, Azide-free, HRP) - LS-C249507 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa574-673) - LS-C306510 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BBS7 Antibody - LS-C309589 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa72-99) - LS-C319787 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BBS7 Antibody (aa73-99) - LS-C159168 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BBS7 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The BBS7 antibody detected the BBS7 protein (arrow).

Anti-BBS7 Antibody (aa263-540) - LS-C186098 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. BBS7 antibody diluted at 1:1000.

Anti-BBS7 Antibody (aa73-99, AP) - LS-C233073 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

BBS7 Antibody - NBP1-88690 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BBS7 Antibody [NBP1-88690] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

BBS7 Antibody - H00055212-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BBS7 Antibody [H00055212-D01P] - Analysis of BBS7 expression in mouse lung.

BBS7 Antibody - NBP1-32754 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BBS7 Antibody [NBP1-32754] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:1000.

BBS7 Antibody (2H6) - H00055212-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H6
Western Blot: BBS7 Antibody (2H6) [H00055212-M01] - Antibody Reactive Against Recombinant Protein.

BBS7 Antibody - H00055212-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BBS7 Antibody [H00055212-B01] - analysis of BBS7 expression in transfected 293T cell line by BBS7 MaxPab polyclonal antibody (B01). Lane 1: BBS7 transfected lysate (80.40 KDa). Lane 2: Non-transfected lysate.
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