BBS7

Gene Symbol	BBS7
Entrez Gene	55212
Alt Symbol	BBS2L1
Species	Human
Gene Type	protein-coding
Description	Bardet-Biedl syndrome 7
Other Description	BBS2-like 1|Bardet-Biedl syndrome 7 protein
Swissprots	Q8N581 Q8IWZ6 Q9NVI4 Q4W5P8
Accessions	AAY40970 EAX05244 EAX05245 Q8IWZ6 AF521643 AAO16025 AF521644 AAO16026 AI220177 AK001577 BAA91767 AK308076 AK309803 BC032691 AAH32691 BF431967 BG720664 BM998707 BQ940332 BX510161 DB139794 DQ890888 ABM81814 DQ896810 ABM87809 XM_005263106 XP_005263163 XM_011532079 XP_011530381 XM_011532080 XP_011530382 XM_011532081 XP_011530383 NM_018190 NP_060660 NM_176824 NP_789794
Function	The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. {ECO:0000269|PubMed:17574030, ECO:0000269|PubMed:22072986}.
Subcellular Location	Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Tissue Specificity	Isoform 2 is ubiquitously expressed. Isoform 1 is expressed in retina, lung, liver, testis, ovary, prostate, small intestine, liver, brain, heart and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BBS7 full length protein - ab163016 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BBS7 protein fragment - ab163017 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BBS7 Antibody Blocking Peptide - LS-E5015 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BBS7 Protein - H00055212-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BBS7 Protein - H00055212-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BBS7-Antibody-N-term-Blocking-Peptide - BP17417a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Bbs7 Peptide - AC21-2172-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

BBS7 - H00055212-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BBS7 - H00055212-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BBS7 - H00055212-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BBS7 - H00055212-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BBS7 fusion protein - Ag4601 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BBS7 fusion protein - ag4314 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Bardet-Biedl syndrome 7 protein(BBS7) - CSB-YP814219HU CSB-EP814219HU CSB-BP814219HU CSB-MP814219HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BBS7 (transcript variant 2) - TP307504 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BBS7, Peptide - MBS427791 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

BBS7 Recombinant Protein Antigen - NBP1-88690PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BBS7 Peptide, Human - M34GP01346H from Creative Peptides Category Peptide Source Synthetic. Species Human

BBS7 Antibody - SH-A10555 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

Bardet-Biedl syndrome 7 protein (BBS7), Recombinant Protein - MBS1336052 from MyBioSource Category Protein Prices $1,525.00, $1,525.00, $1,750.00, $1,750.00, $2,610.00, $2,610.00, $3,055.00, $3,055.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human BBS7 Protein, GST-tagged - BBS7-110H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human BBS7 Protein, GST-tagged - BBS7-111H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human BBS7 Protein, MYC/DDK-tagged - BBS7-2377H from Creative Biomart Category Protein Source HEK293 Species Human

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