| Gene Symbol |
BNIP1
|
| Entrez Gene |
662
|
| Alt Symbol |
NIP1, SEC20, TRG-8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
BCL2/adenovirus E1B 19kDa interacting protein 1
|
| Other Description |
BCL2/adenovirus E1B 19 kDa protein-interacting protein 1|transformation-related gene 8 protein|vesicle transport protein SEC20
|
| Swissprots |
O75623 D3DQM3 D3DQM4 Q96FG4 O75622 D3DQM5 O75624 Q12981 Q6K044 D3DQM6
|
| Accessions |
AAO61090 EAW61405 EAW61406 EAW61407 EAW61408 EAW61409 EAW61410 EAW61411 EAW61412 EAW61413 Q12981 AF083956 AAC33124 AF083957 AAC33125 AF083958 AAC33126 AU311051 AY216799 AAO91805 BC010959 AAH10959 BP384034 HQ448190 ADQ32671 U15172 AAC00020 XM_011534638 XP_011532940 XM_011534639 XP_011532941 NM_001205 NP_001196 NM_013978 NP_053581 NM_013979 NP_053582 NM_013980 NP_053583
|
| Function |
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. {ECO:0000269|PubMed:15272311, ECO:0000269|PubMed:21931693}.
|
| Subcellular Location |
Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
|
| Tissue Specificity |
Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. {ECO:0000269|PubMed:10217402}.
|
| Top Pathways |
SNARE interactions in vesicular transport
|
![Western Blot: BNIP1 Overexpression Lysate (Adult Normal) [NBL1-08012] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BNIP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2945_BNIP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08012-img0002.jpg)