BNIP1
| Gene Symbol | BNIP1 |
|---|---|
| Entrez Gene | 662 |
| Alt Symbol | NIP1, SEC20, TRG-8 |
| Species | Human |
| Gene Type | protein-coding |
| Description | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| Other Description | BCL2/adenovirus E1B 19 kDa protein-interacting protein 1|transformation-related gene 8 protein|vesicle transport protein SEC20 |
| Swissprots | O75623 D3DQM3 D3DQM4 Q96FG4 O75622 D3DQM5 O75624 Q12981 Q6K044 D3DQM6 |
| Accessions | AAO61090 EAW61405 EAW61406 EAW61407 EAW61408 EAW61409 EAW61410 EAW61411 EAW61412 EAW61413 Q12981 AF083956 AAC33124 AF083957 AAC33125 AF083958 AAC33126 AU311051 AY216799 AAO91805 BC010959 AAH10959 BP384034 HQ448190 ADQ32671 U15172 AAC00020 XM_011534638 XP_011532940 XM_011534639 XP_011532941 NM_001205 NP_001196 NM_013978 NP_053581 NM_013979 NP_053582 NM_013980 NP_053583 |
| Function | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. {ECO:0000269|PubMed:15272311, ECO:0000269|PubMed:21931693}. |
| Subcellular Location | Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. |
| Tissue Specificity | Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. {ECO:0000269|PubMed:10217402}. |
| Top Pathways | SNARE interactions in vesicular transport |
BNIP-1 CRISPR/Cas9 KO Plasmid (h) - sc-408712 from Santa Cruz Biotechnology
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BNIP-1 HDR Plasmid (h) - sc-408712-HDR from Santa Cruz Biotechnology
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BNIP-1 Double Nickase Plasmid (h) - sc-408712-NIC from Santa Cruz Biotechnology
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BNIP-1 Double Nickase Plasmid (h2) - sc-408712-NIC-2 from Santa Cruz Biotechnology
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BNIP-1 CRISPR Activation Plasmid (h) - sc-408712-ACT from Santa Cruz Biotechnology
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BNIP-1 CRISPR Activation Plasmid (h2) - sc-408712-ACT-2 from Santa Cruz Biotechnology
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BNIP-1 Lentiviral Activation Particles (h) - sc-408712-LAC from Santa Cruz Biotechnology
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BNIP-1 Lentiviral Activation Particles (h2) - sc-408712-LAC-2 from Santa Cruz Biotechnology
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BNIP-1 siRNA (h) - sc-36067 from Santa Cruz Biotechnology
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BNIP-1 shRNA Plasmid (h) - sc-36067-SH from Santa Cruz Biotechnology
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BNIP-1 shRNA (h) Lentiviral Particles - sc-36067-V from Santa Cruz Biotechnology
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BNIP1 RNAi - H00000662-R01 from Novus Biologicals
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BNIP1 RNAi - H00000662-R02 from Novus Biologicals
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BNIP1 RNAi - H00000662-R03 from Novus Biologicals
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MISSION® esiRNA - EHU080161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4017 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4017 from Sigma-Aldrich
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BNIP1 siRNA (Human) - CRH0457 from Cohesion Biosciences
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BNIP1 RNAi - H00000662-R04 from Novus Biologicals
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BNIP1 - MBS8201870 from MyBioSource
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shRNA set against Human BNIP1 (NM_001205.2) - SHH247250 from Creative biogene
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shRNA set against Human BNIP1(NM_013980.2) - SHG102637 from Creative biogene
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shRNA set against Human BNIP1(NM_001205.2) - SHG102655 from Creative biogene
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shRNA set against Human BNIP1(NM_013978.2) - SHG102691 from Creative biogene
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shRNA set against Human BNIP1(NM_013979.2) - SHG102751 from Creative biogene
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