| Gene Symbol |
RNF103
|
| Entrez Gene |
7844
|
| Alt Symbol |
HKF-1, KF-1, KF1, ZFP-103, ZFP103
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 103
|
| Other Description |
E3 ubiquitin-protein ligase RNF103|zinc finger protein 103 homolog|zinc finger protein expressed in cerebellum
|
| Swissprots |
Q53SU6 B2RAG4 Q8IVB9 O00237 A6NFV6
|
| Accessions |
AAX93079 BAB20900 EAW99446 EAW99447 O00237 AI150469 AK122978 AK314180 BAG36861 AW964704 BC022477 BC035053 AAH35053 BC110333 AAI10334 BQ018198 CA312650 CD109559 D76444 BAA19739 DA816879 EU446737 ABZ92266 NM_001198951 NP_001185880 NM_001198952 NP_001185881 NM_005667 NP_005658
|
| Function |
Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway. {ECO:0000269|PubMed:10500182, ECO:0000269|PubMed:18675248}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:18675248}; Multi-pass membrane protein {ECO:0000269|PubMed:18675248}.
|
| Tissue Specificity |
Highly expressed in the normal cerebellum but not in the cerebral cortex. {ECO:0000269|PubMed:9070305}.
|