Gene Symbol | RNF103 |
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Entrez Gene | 7844 |
Alt Symbol | HKF-1, KF-1, KF1, ZFP-103, ZFP103 |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 103 |
Other Description | E3 ubiquitin-protein ligase RNF103|zinc finger protein 103 homolog|zinc finger protein expressed in cerebellum |
Swissprots | Q53SU6 B2RAG4 Q8IVB9 O00237 A6NFV6 |
Accessions | AAX93079 BAB20900 EAW99446 EAW99447 O00237 AI150469 AK122978 AK314180 BAG36861 AW964704 BC022477 BC035053 AAH35053 BC110333 AAI10334 BQ018198 CA312650 CD109559 D76444 BAA19739 DA816879 EU446737 ABZ92266 NM_001198951 NP_001185880 NM_001198952 NP_001185881 NM_005667 NP_005658 |
Function | Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway. {ECO:0000269|PubMed:10500182, ECO:0000269|PubMed:18675248}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18675248}; Multi-pass membrane protein {ECO:0000269|PubMed:18675248}. |
Tissue Specificity | Highly expressed in the normal cerebellum but not in the cerebral cortex. {ECO:0000269|PubMed:9070305}. |
RNF103 CRISPR/Cas9 KO Plasmid (h) - sc-417796 from Santa Cruz Biotechnology
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RNF103 HDR Plasmid (h) - sc-417796-HDR from Santa Cruz Biotechnology
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RNF103 Double Nickase Plasmid (h) - sc-417796-NIC from Santa Cruz Biotechnology
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RNF103 Double Nickase Plasmid (h2) - sc-417796-NIC-2 from Santa Cruz Biotechnology
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RNF103 CRISPR Activation Plasmid (h) - sc-417796-ACT from Santa Cruz Biotechnology
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RNF103 CRISPR Activation Plasmid (h2) - sc-417796-ACT-2 from Santa Cruz Biotechnology
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RNF103 Lentiviral Activation Particles (h) - sc-417796-LAC from Santa Cruz Biotechnology
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RNF103 Lentiviral Activation Particles (h2) - sc-417796-LAC-2 from Santa Cruz Biotechnology
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RNF103 siRNA (h) - sc-94784 from Santa Cruz Biotechnology
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RNF103 shRNA Plasmid (h) - sc-94784-SH from Santa Cruz Biotechnology
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RNF103 shRNA (h) Lentiviral Particles - sc-94784-V from Santa Cruz Biotechnology
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KF1 RNAi - H00007844-R01V from Novus Biologicals
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KF1 RNAi - H00007844-R01 from Novus Biologicals
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MISSION® esiRNA - EHU018161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18363 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18363 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04480 from Sigma-Aldrich
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RNF103 siRNA (Human) - CRH5291 from Cohesion Biosciences
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RNF103 - MBS8208112 from MyBioSource
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shRNA set against Human RNF103 (NM_005667.3) - SHH396500 from Creative biogene
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Human RNF103 siRNA - orb265793 from Biorbyt
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RNF103 shRNA Plasmid (Human) - CHH5291 from Cohesion Biosciences
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RNF103 miRNA 3'UTR clone - MiUTR3H-05041 from Creative biogene
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