| Gene Symbol |
ZACN
|
| Entrez Gene |
353174
|
| Alt Symbol |
L2, LGICZ, LGICZ1, ZAC, ZAC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc activated ligand-gated ion channel
|
| Other Description |
ligand-gated ion channel subunit|ligand-gated ion channel zinc-activated 1|ligand-gated ion channel, zinc activated 1|ligand-gated ion-channel receptor L2|zinc activated ligand-gated ion channel 1|zinc-activated ligand-gated ion channel
|
| Swissprots |
Q2TB29 Q86YW4 Q401N2 Q6ZWK3
|
| Accessions |
EAW89365 EAW89366 Q401N2 AB223030 BAE19924 AF512521 AAO20969 AK122638 BC110596 BC110597 AAI10598 DB119720 XM_011524746 XP_011523048 NM_180990 NP_851321
|
| Function |
Zinc-activated ligand-gated ion channel. {ECO:0000269|PubMed:12381728}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:16083862}; Multi-pass membrane protein {ECO:0000269|PubMed:16083862}.
|
| Tissue Specificity |
Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus. {ECO:0000269|PubMed:12381728, ECO:0000269|PubMed:16083862}.
|
![Western Blot: ZACN Overexpression Lysate (Adult Normal) [NBP2-04942] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZACN.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5072_ZACN%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04942-img0001.jpg)