Gene Symbol | ZACN |
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Entrez Gene | 353174 |
Alt Symbol | L2, LGICZ, LGICZ1, ZAC, ZAC1 |
Species | Human |
Gene Type | protein-coding |
Description | zinc activated ligand-gated ion channel |
Other Description | ligand-gated ion channel subunit|ligand-gated ion channel zinc-activated 1|ligand-gated ion channel, zinc activated 1|ligand-gated ion-channel receptor L2|zinc activated ligand-gated ion channel 1|zinc-activated ligand-gated ion channel |
Swissprots | Q2TB29 Q86YW4 Q401N2 Q6ZWK3 |
Accessions | EAW89365 EAW89366 Q401N2 AB223030 BAE19924 AF512521 AAO20969 AK122638 BC110596 BC110597 AAI10598 DB119720 XM_011524746 XP_011523048 NM_180990 NP_851321 |
Function | Zinc-activated ligand-gated ion channel. {ECO:0000269|PubMed:12381728}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16083862}; Multi-pass membrane protein {ECO:0000269|PubMed:16083862}. |
Tissue Specificity | Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus. {ECO:0000269|PubMed:12381728, ECO:0000269|PubMed:16083862}. |
LGICZ1 CRISPR/Cas9 KO Plasmid (h) - sc-415669 from Santa Cruz Biotechnology
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LGICZ1 HDR Plasmid (h) - sc-415669-HDR from Santa Cruz Biotechnology
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LGICZ1 Double Nickase Plasmid (h) - sc-415669-NIC from Santa Cruz Biotechnology
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LGICZ1 Double Nickase Plasmid (h2) - sc-415669-NIC-2 from Santa Cruz Biotechnology
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LGICZ1 CRISPR Activation Plasmid (h) - sc-415669-ACT from Santa Cruz Biotechnology
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LGICZ1 CRISPR Activation Plasmid (h2) - sc-415669-ACT-2 from Santa Cruz Biotechnology
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LGICZ1 Lentiviral Activation Particles (h) - sc-415669-LAC from Santa Cruz Biotechnology
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LGICZ1 Lentiviral Activation Particles (h2) - sc-415669-LAC-2 from Santa Cruz Biotechnology
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LGICZ1 siRNA (h) - sc-93908 from Santa Cruz Biotechnology
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LGICZ1 shRNA Plasmid (h) - sc-93908-SH from Santa Cruz Biotechnology
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LGICZ1 shRNA (h) Lentiviral Particles - sc-93908-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN23039 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23039 from Sigma-Aldrich
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ZACN siRNA (Human) - CRJ7576 from Cohesion Biosciences
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ZACN RNAi - H00353174-R01 from Novus Biologicals
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ZACN - MBS8210834 from MyBioSource
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shRNA set against Human ZACN (NM_180990.3) - SHH448760 from Creative biogene
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Human ZACN siRNA - orb278077 from Biorbyt
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ZACN shRNA Plasmid (Human) - CHJ7576 from Cohesion Biosciences
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ZACN miRNA 3'UTR clone - MiUTR4H-TG09970 from Creative biogene
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