| Gene Symbol |
VPS11
|
| Entrez Gene |
55823
|
| Alt Symbol |
END1, PEP5, RNF108, hVPS11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 11 homolog (S. cerevisiae)
|
| Other Description |
RING finger protein 108|vacuolar protein sorting-associated protein 11 homolog
|
| Swissprots |
Q9H6D9 Q96EP8 Q9HCS6 Q8WY89 Q9H270
|
| Accessions |
EAW67444 EAW67445 EAW67446 Q9H270 AB027508 BAA95163 AF258558 AAG23761 AF308800 AAG34677 AK023279 AK026012 BAB15320 AK056701 BAG51790 AK223158 BAD96878 AK302973 BAH13865 AL834218 CAH56401 BC012051 AAH12051 BC065563 AAH65563 BI561271 XM_011542898 XP_011541200 XM_011542899 XP_011541201 XM_011548788 XP_011547090 XM_011548789 XP_011547091 XR_947859 XR_953220 NM_001290185 NP_001277114 NM_021729 NP_068375
|
| Function |
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. {ECO:0000269|PubMed:11382755}.
|
| Subcellular Location |
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle.
|
| Tissue Specificity |
Ubiquitous. Expression was highest in heart and low in lung.
|
![Western Blot: VPS11 Overexpression Lysate (Adult Normal) [NBL1-17736] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VPS11.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6913_VPS11%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17736-img0002.jpg)