Gene Symbol | VPS11 |
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Entrez Gene | 55823 |
Alt Symbol | END1, PEP5, RNF108, hVPS11 |
Species | Human |
Gene Type | protein-coding |
Description | vacuolar protein sorting 11 homolog (S. cerevisiae) |
Other Description | RING finger protein 108|vacuolar protein sorting-associated protein 11 homolog |
Swissprots | Q9H6D9 Q96EP8 Q9HCS6 Q8WY89 Q9H270 |
Accessions | EAW67444 EAW67445 EAW67446 Q9H270 AB027508 BAA95163 AF258558 AAG23761 AF308800 AAG34677 AK023279 AK026012 BAB15320 AK056701 BAG51790 AK223158 BAD96878 AK302973 BAH13865 AL834218 CAH56401 BC012051 AAH12051 BC065563 AAH65563 BI561271 XM_011542898 XP_011541200 XM_011542899 XP_011541201 XM_011548788 XP_011547090 XM_011548789 XP_011547091 XR_947859 XR_953220 NM_001290185 NP_001277114 NM_021729 NP_068375 |
Function | May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. {ECO:0000269|PubMed:11382755}. |
Subcellular Location | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. |
Tissue Specificity | Ubiquitous. Expression was highest in heart and low in lung. |
VPS11 CRISPR/Cas9 KO Plasmid (h) - sc-408387 from Santa Cruz Biotechnology
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VPS11 HDR Plasmid (h) - sc-408387-HDR from Santa Cruz Biotechnology
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VPS11 Double Nickase Plasmid (h) - sc-408387-NIC from Santa Cruz Biotechnology
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VPS11 Double Nickase Plasmid (h2) - sc-408387-NIC-2 from Santa Cruz Biotechnology
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VPS11 CRISPR Activation Plasmid (h) - sc-408387-ACT from Santa Cruz Biotechnology
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VPS11 CRISPR Activation Plasmid (h2) - sc-408387-ACT-2 from Santa Cruz Biotechnology
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VPS11 Lentiviral Activation Particles (h) - sc-408387-LAC from Santa Cruz Biotechnology
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VPS11 Lentiviral Activation Particles (h2) - sc-408387-LAC-2 from Santa Cruz Biotechnology
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VPS11 siRNA (h) - sc-76900 from Santa Cruz Biotechnology
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VPS11 shRNA Plasmid (h) - sc-76900-SH from Santa Cruz Biotechnology
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VPS11 shRNA (h) Lentiviral Particles - sc-76900-V from Santa Cruz Biotechnology
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VPS11 RNAi - H00055823-R01 from Novus Biologicals
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MISSION® esiRNA - EHU037911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22705 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22705 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02726 from Sigma-Aldrich
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VPS11 siRNA (Human) - CRJ0950 from Cohesion Biosciences
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VPS11 - MBS8234011 from MyBioSource
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shRNA set against Human VPS11 (NM_021729.4) - SHH444772 from Creative biogene
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shRNA set against Human VPS11(NM_021729.4) - SHL126872 from Creative biogene
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Human VPS11 siRNA - orb271451 from Biorbyt
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VPS11 shRNA Plasmid (Human) - CHJ0950 from Cohesion Biosciences
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VPS11 miRNA 3'UTR clone - MiUTR1H-11133 from Creative biogene
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