ZBTB7B

Gene Symbol ZBTB7B
Entrez Gene 51043
Alt Symbol CKROX, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX
Species Human
Gene Type protein-coding
Description zinc finger and BTB domain containing 7B
Other Description T-helper-inducing POZ/Krueppel-like factor|krueppel-related zinc finger protein cKrox|zinc finger and BTB domain containing 15|zinc finger and BTB domain-containing protein 7B|zinc finger protein 67 homolog|zinc finger protein 857B|zinc finger protein Th-POK
Swissprots D3DV83 J3KQQ3 Q96EP2 Q68DR2 B4E3K5 O15156
Accessions EAW53149 EAW53150 EAW53151 O15156 AF007833 AAC51847 AI270090 AK127884 AK291619 BAF84308 AK304762 BAG65517 AW663133 BC012070 AAH12070 BC128176 BF510901 BM801567 BX114870 CK820289 CR749303 CAH18158 CV572166 DA970906 DB241444 EU446494 ABZ92023 EU832462 ACE87634 EU832510 ACE87682 EU832516 ACE87688 EU832544 ACE86946 EU832591 ACE86993 EU832597 ACE86999 XM_006711349 XP_006711412 XM_006711353 XP_006711416 XM_006711354 XP_006711417 XM_006711356 XP_006711419 XM_006711357 XP_006711420 XM_006711358 XP_006711421 XM_006711359 XP_006711422 XM_011509598 XP_011507900 XM_011509599 XP_011507901 NM_001252406 NP_001239335 NM_001256455 NP_001243384 NR_045515 NR_046206 NR_049765
Function Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.

ThPOK (D9V5T) Rabbit mAb - 13205 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9V5T
Western blot analysis of mouse CD4+ T cells and mouse CD8+ T cells using ThPOK (D9V5T) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

TH-POK (A-4) - sc-376250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TH-POK (A-4): sc-376250. Western blot analysis of TH-POK expression in non-transfected: sc-117752 (A) and mouse TH-POK transfected: sc-124029 (B) 293T whole cell lysates and HeLa nuclear extract (C).

TH-POK (C-8) - sc-398509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TH-POK (C-8): sc-398509. Western blot analysis of TH-POK expression in non-transfected: sc-117752 (A) and mouse TH-POK transfected: sc-124029 (B) 293T whole cell lysates and HeLa nuclear extract (C).

TH-POK (G-16) - sc-79125 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TH-POK (S-20) - sc-79127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TH-POK (S-20): sc-79127. Western blot analysis of TH-POK expression in non-transfected: sc-117752 (A) and mouse TH-POK transfected: sc-124029 (B) 293T whole cell lysates.

TH-POK (H-107) - sc-292625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TH-POK (H-107): sc-292625. Western blot analysis of TH-POK expression in A-431 whole cell lysate.

TH-POK (6) - sc-136347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TH-POK (6): sc-136347. Western blot analysis of TH-POK expression in A-431 whole cell lysate.

Anti-ThPok antibody - ab70991 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ThPok antibody (ab70991) at 1/60 dilution + mouse brain tissue lysates at 35 µg

Anti-ThPok antibody - ab23388 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ThPok antibody - ab186996 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-ThPok antibody (ab186996) at 1/1000 dilution + Jurkat total cell extracts

Anti-ThPok antibody - ab111211 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111211, at 3.75 µg/ml, staining ThPok in formalin fixed, paraffin embedded Human adrenal tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.

Anti-ThPok antibody [7C12] - ab93922 from Abcam

Host Mouse
Clonality Monoclonal
Clone 7C12
All lanes : Anti-ThPok antibody [7C12] (ab93922) at 1/500 dilutionLane 1 : HEK293 cell lysateLane 2 : HEK293 cell lysate

Anti-ZBTB7B / HcKrox Antibody (aa78-172, clone GL-3/5E11) - LS-C189844 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone GL-3/5E11

Anti-ZBTB7B / HcKrox Antibody (aa314-343, APC) - LS-C273910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa314-343, AP) - LS-C273911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa313-362) - LS-C31250 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ZBTB7B antibody LS-C31250 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-ZBTB7B / HcKrox Antibody (aa314-343, Biotin) - LS-C273913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa314-343, FITC) - LS-C273914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa314-343, Azide-free, HRP) - LS-C273916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa314-343, PE) - LS-C273931 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (Internal, AP) - LS-C284402 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (aa181-210) - LS-C99174 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZBTB7B antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-ZBTB7B / HcKrox Antibody (Internal, APC) - LS-C284403 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (Internal, Biotin) - LS-C284404 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7B / HcKrox Antibody (Internal, FITC) - LS-C284407 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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