ABCB6

Gene Symbol ABCB6
Entrez Gene 10058
Alt Symbol ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
Other Description ATP-binding cassette half-transporter|ATP-binding cassette sub-family B member 6, mitochondrial|P-glycoprotein-related protein|mitochondrial ABC transporter 3|mt-ABC transporter 3|ubiquitously-expressed mammalian ABC half transporter
Swissprots Q9HAQ7 Q59GQ5 Q6ZME6 Q9HAQ6 Q49A66 O75542 Q96ME8 Q9NP58
Accessions AAG33618 BAA96733 BAN91499 BAN91500 BAN91501 BAN91502 BAN91503 BAN91504 EAW70694 EAW70695 EAW70696 EAW70697 EAW70698 EAW70699 EAW70700 EAW70701 EAW70702 EAW70703 EAW70704 EAW70705 Q9NP58 AF070598 AAC28653 AF076775 AAF75107 AF308472 AAG33617 AJ289233 CAB95766 AK026067 AK057026 BAB71347 AK172812 BAD18782 AK303230 BAG64317 AL560811 AW664349 BC000559 AAH00559 BC043423 AAH43423 DQ891876 ABM82802 DQ895063 ABM85989 U66673 NM_005689 NP_005680
Function Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:17006453}.
Subcellular Location Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome {ECO:0000250}. Note=localized to the endosome- like compartement and dendrite tips.
Tissue Specificity Widely expressed. High expression is detected in the retinal epithelium. {ECO:0000269|PubMed:10837493, ECO:0000269|PubMed:22226084}.
Top Pathways ABC transporters

ABCB6 (G-10) - sc-365930 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ABCB6 (G-10): sc-365930. Western blot analysis of ABCB6 expression in HeLa whole cell lysate.

ABCB6 (L-12) - sc-107367 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ABCB6 (24.39) - sc-135727 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

ABCB6 (H-300) - sc-98685 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ABCB6 (H-300): sc-98685. Western blot analysis of ABCB6 expression in Hep G2 whole cell lysate.

ABCB6 (61.5) - sc-135726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-ABCB6 antibody - ab47837 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilutionLane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 proteinLane 2 : KB cell lysate without a vector insert

Anti-ABCB6 antibody - C-terminal - ab194409 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-ABCB6 antibody - C-terminal (ab194409) at 1/500 dilution + NIH3T3 cell lysate at 50 µgSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-ABCB6 Antibody (aa827-842) - LS-C2975 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCB6 Antibody (aa260-301, Biotin) - LS-C183729 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCB6 Antibody (aa743-842) - LS-C306017 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ABCB6 Antibody (aa260-301) - LS-C190417 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ABCB6 Antibody (aa260-301) - LS-C190416 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ABCB6 Antibody (aa431-480) - LS-C116204 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ABCB6 antibody LS-C116204 Western blot of HeLa lysate.

Anti-ABCB6 Antibody (aa440-455) - LS-C19004 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of anti-ABCB6 antibody (right panel, lane B6) shows detection of Flag-tagged human ABCB6 protein at 104 kD and a truncated form of the protein at 79 kD (arrowheads). The antibody successfully detected ABCB6 in KB cells transfected with the ABCB6 protein. A Lysate prepared from KB cells without a vector insert (CV lane) should no reactivity with the antibody. The left panel shows a similar staining pattern using an anti-Flag antibody as a positive control. The membrane was probe.

Anti-ABCB6 Antibody (aa818-842) - LS-C312873 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ABCB6 antibody. IHC(P): Human Breast Cancer Tissue.

ABCB6 Antibody - NBP1-57029 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Antibody - H00010058-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ABCB6 Antibody [H00010058-A01] - Western Blot analysis of ABCB6 expression in HeLa ( Cat # L013V1 ).

ABCB6 Antibody - NBP1-91642 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ABCB6 Antibody [NBP1-91642] - Staining of human cell line U-251 MG shows localization to the Golgi apparatus.

ABCB6 Polyclonal Antibody - bs-1224R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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ABCB6 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-1224R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-1224R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-1224R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-1224R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Polyclonal Antibody, Cy3 Conjugated - bs-1224R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ABCB6 Polyclonal Antibody, Cy5 Conjugated - bs-1224R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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