PLXDC1

Gene Symbol PLXDC1
Entrez Gene 57125
Alt Symbol TEM3, TEM7
Species Human
Gene Type protein-coding
Description plexin domain containing 1
Other Description 2410003I07Rik|plexin domain-containing protein 1|tumor endothelial marker 3|tumor endothelial marker 7
Swissprots Q8IUK5 Q5QCZ7 Q5QCZ9 Q5QCZ8 Q9HCT9 B2R7I8
Accessions EAW60551 EAW60552 EAW60553 Q8IUK5 AF070526 AF279144 AAG00869 AF378753 AAL11990 AK093589 BAG52742 AK127539 BAC87025 AK303699 BAG64685 AK312999 BAG35835 AL833517 AY704670 AAV85657 AY704671 AAV85658 AY704672 AAV85659 BC036059 AAH36059 DA205327 EU832116 ACE87466 EU832210 ACE86780 NM_020405 NP_065138
Function Plays a critical role in endothelial cell capillary morphogenesis. {ECO:0000250}.
Subcellular Location Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. {ECO:0000269|PubMed:10947988, ECO:0000269|PubMed:11559528, ECO:0000269|PubMed:17560052, ECO:0000269|PubMed:18316703}.

TEM7 CRISPR/Cas9 KO Plasmid (h) - sc-406089 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 HDR Plasmid (h) - sc-406089-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 Double Nickase Plasmid (h) - sc-406089-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 Double Nickase Plasmid (h2) - sc-406089-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 CRISPR Activation Plasmid (h) - sc-406089-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 CRISPR Activation Plasmid (h2) - sc-406089-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 Lentiviral Activation Particles (h) - sc-406089-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 Lentiviral Activation Particles (h2) - sc-406089-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM7 siRNA (h) - sc-61663 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM7 shRNA Plasmid (h) - sc-61663-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM7 shRNA (h) Lentiviral Particles - sc-61663-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM7/PLXDC1 RNAi - H00057125-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: TEM7/PLXDC1 RNAi [H00057125-R01V] - Analysis of PLXDC1 over-expressed 293 cell line, cotransfected with PLXDC1 Validated Chimera RNAi or non-transfected control. Blot probed with H00057125-M01. GAPDH (36.1 kDa) used as loading control.

TEM7/PLXDC1 RNAi - H00057125-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU036711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1087 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1087 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1086 from Sigma-Aldrich

Category ZFN Kit
Prices $6,000.00
Sizes 1 kt

PLXDC1 siRNA (Human) - CRJ1340 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLXDC1 (NM_020405.4) - SHH378168 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLXDC1 siRNA - orb271841 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLXDC1 shRNA Plasmid (Human) - CHJ1340 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLXDC1 miRNA 3'UTR clone - MiUTR4H-TG06796 from Creative biogene

Species Reactivities Human
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