Gene Symbol | TPCN1 |
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Entrez Gene | 53373 |
Alt Symbol | TPC1 |
Species | Human |
Gene Type | protein-coding |
Description | two pore segment channel 1 |
Other Description | two pore calcium channel protein 1|two-pore channel 1|two-pore segment channel 1|voltage-dependent calcium channel protein TPC1 |
Swissprots | Q8NC20 Q86XS9 A7E258 Q9ULQ1 |
Accessions | EAW98046 EAW98047 Q9ULQ1 AB032995 BAA86483 AK000619 BAA91290 AK025838 AK057414 AK075071 BAC11385 AK093490 BAG52729 AK295022 BAH11951 AK296268 BAH12298 AY083666 AAM01199 BC007419 BC068001 BC069234 BC110885 BC136795 AAI36796 BC136796 AAI36797 BC142664 AAI42665 BC150203 AAI50204 BC152423 AAI52424 DA777641 XM_005253905 XP_005253962 XM_005253906 XP_005253963 XM_011538489 XP_011536791 XM_011538490 XP_011536792 XM_011538492 XP_011536794 XM_011538493 XP_011536795 XM_011538494 XP_011536796 XR_243017 NM_001143819 NP_001137291 NM_001301214 NP_001288143 NM_017901 NP_060371 |
Function | Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane. {ECO:0000269|PubMed:19620632}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:19620632}; Multi-pass membrane protein {ECO:0000269|PubMed:19620632}. Endosome membrane {ECO:0000269|PubMed:19620632}; Multi-pass membrane protein {ECO:0000269|PubMed:19620632}. |
Tissue Specificity | Highest expression found in the heart and kidney, and lowest expression found in the spleen. {ECO:0000269|PubMed:10574461}. |
TPCN1 (C-14) - sc-67973 from Santa Cruz Biotechnology
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Anti-TPCN1 antibody - ab87516 from Abcam
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Anti-TPC1 / TPCN1 Antibody (aa750-800) - LS-C95183 from LifeSpan Bioscience
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Anti-TPC1 / TPCN1 Antibody (aa750-800) - LS-C95184 from LifeSpan Bioscience
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Anti-TPC1 / TPCN1 Antibody (aa71-120) - LS-C110014 from LifeSpan Bioscience
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TPCN1 Antibody - NBP1-46381 from Novus Biologicals
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TPCN1 Antibody - NBP1-83642 from Novus Biologicals
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TPCN1 Antibody - NBP1-20219 from Novus Biologicals
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Anti-TPCN1, (N-terminal) antibody produced in rabbit - SAB2104213 from Sigma-Aldrich
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Anti-TPCN1 antibody produced in rabbit - HPA039757 from Sigma-Aldrich
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TPCN1 antibody - N-terminal region (ARP35276_P050) - ARP35276_P050 from Aviva Systems Biology
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TPCN1 antibody - 70R-5158 from Fitzgerald
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TPCN1 antibody - orb186396 from Biorbyt
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TPCN1 antibody - 23758-1-AP from Acris Antibodies
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TPCN1 antibody - 23758-1-AP from Proteintech Group
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TPCN1 Antibody - GWB-MM064A from Genway Biotech
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Rabbit anti-Human TPCN1 polyclonal antibody - DPABH-11899 from Creative Diagnostics
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Anti-TPCN1 (aa 72-121) polyclonal antibody - DPABH-19383 from Creative Diagnostics
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TPCN1, Polyclonal Antibody - MBS540423 from MyBioSource
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TPCN1 Antibody - TPC1-101AP from FabGennix
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TPCN1-antibody-N-terminal-region-AI10812 - AI10812 from Abgent, a WuXi AppTec company
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TPCN1, Polyclonal Antibody - MBS5300733 from MyBioSource
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TPCN1 - A9577 from NeoScientific
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TPCN1 Polyclonal Antibody - A9577 from ABclonal
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TPCN1 Antibody - abx124659 from Abbexa
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