| Gene Symbol |
HIST1H2BK
|
| Entrez Gene |
85236
|
| Alt Symbol |
H2B/S, H2BFAiii, H2BFT, H2BK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2bk
|
| Other Description |
H2B K|H2B histone family, member T|HIRA-interacting protein 1|histone 1, H2bk|histone H2B type 1-K|histone family member
|
| Swissprots |
A8K7P7 O60814 Q2VPI7
|
| Accessions |
AAN06694 EAX03084 EAX03085 O60814 AJ223352 CAA11276 AK292062 BAF84751 BC000893 AAH00893 BC051872 AAH51872 BC064959 AAH64959 BC108737 AAI08738 DA873786 EU446970 ABZ92499 NM_080593 NP_542160
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|
![Western Blot: HIST1H2BK Overexpression Lysate (Adult Normal) [NBL1-11563] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HIST1H2BK.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1140_HIST1H2BK%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11563-img0002.jpg)