Gene Symbol |
REPS2
|
Entrez Gene |
9185
|
Alt Symbol |
POB1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
RALBP1 associated Eps domain containing 2
|
Other Description |
RALBP1-interacting protein 2|partner of Ral-binding protein 1|partner of RalBP1|ralBP1-associated Eps domain-containing protein 2
|
Swissprots |
Q8NFH8 Q5JNZ8 Q8NFI5 O43428 A6PWZ6
|
Accessions |
EAW98922 EAW98923 Q8NFH8 AB208937 BAD92174 AF010233 AAC02901 AF511533 AAM43933 AF512951 AAM43953 AI221053 AK057127 AK097484 AK298913 BAG61020 XM_005274625 XP_005274682 XM_005274626 XP_005274683 XM_006724523 XP_006724586 XM_011545603 XP_011543905 XM_011545604 XP_011543906 XM_011545605 XP_011543907 XM_011545606 XP_011543908 XM_011545607 XP_011543909 XM_011545608 XP_011543910 XM_011545609 XP_011543911 XM_011545610 XP_011543912 NM_001080975 NP_001074444 NM_004726 NP_004717
|
Function |
Involved in growth factor signaling through its influence on the Ral signaling pathway.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer.
|