Gene Symbol | REPS2 |
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Entrez Gene | 9185 |
Alt Symbol | POB1 |
Species | Human |
Gene Type | protein-coding |
Description | RALBP1 associated Eps domain containing 2 |
Other Description | RALBP1-interacting protein 2|partner of Ral-binding protein 1|partner of RalBP1|ralBP1-associated Eps domain-containing protein 2 |
Swissprots | Q8NFH8 Q5JNZ8 Q8NFI5 O43428 A6PWZ6 |
Accessions | EAW98922 EAW98923 Q8NFH8 AB208937 BAD92174 AF010233 AAC02901 AF511533 AAM43933 AF512951 AAM43953 AI221053 AK057127 AK097484 AK298913 BAG61020 XM_005274625 XP_005274682 XM_005274626 XP_005274683 XM_006724523 XP_006724586 XM_011545603 XP_011543905 XM_011545604 XP_011543906 XM_011545605 XP_011543907 XM_011545606 XP_011543908 XM_011545607 XP_011543909 XM_011545608 XP_011543910 XM_011545609 XP_011543911 XM_011545610 XP_011543912 NM_001080975 NP_001074444 NM_004726 NP_004717 |
Function | Involved in growth factor signaling through its influence on the Ral signaling pathway. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer. |
REPS2 CRISPR/Cas9 KO Plasmid (h) - sc-411251 from Santa Cruz Biotechnology
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REPS2 HDR Plasmid (h) - sc-411251-HDR from Santa Cruz Biotechnology
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REPS2 Double Nickase Plasmid (h) - sc-411251-NIC from Santa Cruz Biotechnology
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REPS2 Double Nickase Plasmid (h2) - sc-411251-NIC-2 from Santa Cruz Biotechnology
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REPS2 CRISPR Activation Plasmid (h) - sc-411251-ACT from Santa Cruz Biotechnology
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REPS2 CRISPR Activation Plasmid (h2) - sc-411251-ACT-2 from Santa Cruz Biotechnology
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REPS2 Lentiviral Activation Particles (h) - sc-411251-LAC from Santa Cruz Biotechnology
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REPS2 Lentiviral Activation Particles (h2) - sc-411251-LAC-2 from Santa Cruz Biotechnology
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REPS2 siRNA (h) - sc-61454 from Santa Cruz Biotechnology
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REPS2 shRNA Plasmid (h) - sc-61454-SH from Santa Cruz Biotechnology
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REPS2 shRNA (h) Lentiviral Particles - sc-61454-V from Santa Cruz Biotechnology
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REPS2 RNAi - H00009185-R01 from Novus Biologicals
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MISSION® esiRNA - EHU075751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18146 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18146 from Sigma-Aldrich
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REPS2 siRNA (Human) - CRH6079 from Cohesion Biosciences
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REPS2 - MBS8231765 from MyBioSource
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shRNA set against Human REPS2 (NM_004726.2) - SHH391960 from Creative biogene
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shRNA set against Human REPS2(NM_004726.2) - SHR163104 from Creative biogene
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shRNA set against Human REPS2(NM_001080975.1) - SHR163140 from Creative biogene
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REPS2 shRNA Plasmid (Human) - CHH6079 from Cohesion Biosciences
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REPS2 miRNA 3'UTR clone - MiUTR1H-08738 from Creative biogene
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