Gene Symbol |
KLRC1
|
Entrez Gene |
3821
|
Alt Symbol |
CD159A, NKG2, NKG2A
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
killer cell lectin-like receptor subfamily C, member 1
|
Other Description |
C-lectin type II protein|CD159 antigen-like family member A|NK cell receptor A|NKG2-1/B activating NK receptor|NKG2-A/B type II integral membrane protein|NKG2-A/B-activating NK receptor|NKG2-A/NKG2-B type II integral membrane protein|natural killer cell lectin|natural killer group protein 2
|
Swissprots |
P26715
|
Accessions |
AAB17133 AAC17488 BAB91356 P26715 AF461812 AAL65234 AK310992 BC012550 AAH12550 BC053840 AAH53840 DB464226 DQ892740 ABM83666 DQ895986 ABM86912 DQ896730 ABM87729 X54867 CAA38649 X54868 CAA38650 NM_001304448 NP_001291377 NM_002259 NP_002250 NM_007328 NP_015567 NM_213657 NP_998822 NM_213658 NP_998823
|
Function |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
|
Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
Tissue Specificity |
Natural killer cells.
|
Top Pathways |
Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation
|