Gene Symbol | KLRC1 |
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Entrez Gene | 3821 |
Alt Symbol | CD159A, NKG2, NKG2A |
Species | Human |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily C, member 1 |
Other Description | C-lectin type II protein|CD159 antigen-like family member A|NK cell receptor A|NKG2-1/B activating NK receptor|NKG2-A/B type II integral membrane protein|NKG2-A/B-activating NK receptor|NKG2-A/NKG2-B type II integral membrane protein|natural killer cell lectin|natural killer group protein 2 |
Swissprots | P26715 |
Accessions | AAB17133 AAC17488 BAB91356 P26715 AF461812 AAL65234 AK310992 BC012550 AAH12550 BC053840 AAH53840 DB464226 DQ892740 ABM83666 DQ895986 ABM86912 DQ896730 ABM87729 X54867 CAA38649 X54868 CAA38650 NM_001304448 NP_001291377 NM_002259 NP_002250 NM_007328 NP_015567 NM_213657 NP_998822 NM_213658 NP_998823 |
Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Natural killer cells. |
Top Pathways | Natural killer cell mediated cytotoxicity, Graft-versus-host disease, Antigen processing and presentation |
NKG2-A CRISPR/Cas9 KO Plasmid (h) - sc-417709 from Santa Cruz Biotechnology
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NKG2-A HDR Plasmid (h) - sc-417709-HDR from Santa Cruz Biotechnology
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NKG2-A Double Nickase Plasmid (h) - sc-417709-NIC from Santa Cruz Biotechnology
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NKG2-A Double Nickase Plasmid (h2) - sc-417709-NIC-2 from Santa Cruz Biotechnology
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NKG2-A CRISPR Activation Plasmid (h) - sc-417709-ACT from Santa Cruz Biotechnology
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NKG2-A CRISPR Activation Plasmid (h2) - sc-417709-ACT-2 from Santa Cruz Biotechnology
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NKG2-A Lentiviral Activation Particles (h) - sc-417709-LAC from Santa Cruz Biotechnology
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NKG2-A Lentiviral Activation Particles (h2) - sc-417709-LAC-2 from Santa Cruz Biotechnology
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NKG2 siRNA (h) - sc-42946 from Santa Cruz Biotechnology
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NKG2 shRNA Plasmid (h) - sc-42946-SH from Santa Cruz Biotechnology
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NKG2 shRNA (h) Lentiviral Particles - sc-42946-V from Santa Cruz Biotechnology
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NKG2-A siRNA (h) - sc-42947 from Santa Cruz Biotechnology
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NKG2-A shRNA Plasmid (h) - sc-42947-SH from Santa Cruz Biotechnology
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NKG2-A shRNA (h) Lentiviral Particles - sc-42947-V from Santa Cruz Biotechnology
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NKG2A/CD159a/KLRC1 RNAi - H00003821-R06 from Novus Biologicals
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NKG2A/CD159a/KLRC1 RNAi - H00003821-R05 from Novus Biologicals
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NKG2A/CD159a/KLRC1 RNAi - H00003821-R07 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN11321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11321 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03944 from Sigma-Aldrich
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KLRC1 siRNA (Human) - CRH2589 from Cohesion Biosciences
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NKG2A/CD159a/KLRC1 RNAi - H00003821-R08 from Novus Biologicals
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shRNA set against Human KLRC1 (NM_002259.4) - SHH326807 from Creative biogene
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KLRC1 shRNA Plasmid (Human) - CHH2589 from Cohesion Biosciences
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KLRC1 miRNA 3'UTR clone - MiUTR3H-01510 from Creative biogene
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