| Gene Symbol |
CD1B
|
| Entrez Gene |
910
|
| Alt Symbol |
CD1, CD1A, R1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD1b molecule
|
| Other Description |
CD1B antigen, b polypeptide|T-cell surface glycoprotein CD1b|cortical thymocyte antigen CD1B|differentiation antigen CD1-alpha-3
|
| Swissprots |
Q5TDL0 Q9UMM2 P29016 Q5TDK9
|
| Accessions |
AAA51936 AAA51940 AAD37579 EAW52841 P29016 AI336342 AK303329 BAG64394 AK303330 BAG64395 AK310617 BC069481 AAH69481 BC074747 AAH74747 BC104216 AAI04217 BC104217 AAI04218 CD687240 HQ448450 ADQ32930 M28826 AAA51939 XM_011510119 XP_011508421 NM_001764 NP_001755
|
| Function |
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts.
|
| Tissue Specificity |
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
|
| Top Pathways |
Hematopoietic cell lineage
|