Gene Symbol | CD1B |
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Entrez Gene | 910 |
Alt Symbol | CD1, CD1A, R1 |
Species | Human |
Gene Type | protein-coding |
Description | CD1b molecule |
Other Description | CD1B antigen, b polypeptide|T-cell surface glycoprotein CD1b|cortical thymocyte antigen CD1B|differentiation antigen CD1-alpha-3 |
Swissprots | Q5TDL0 Q9UMM2 P29016 Q5TDK9 |
Accessions | AAA51936 AAA51940 AAD37579 EAW52841 P29016 AI336342 AK303329 BAG64394 AK303330 BAG64395 AK310617 BC069481 AAH69481 BC074747 AAH74747 BC104216 AAI04217 BC104217 AAI04218 CD687240 HQ448450 ADQ32930 M28826 AAA51939 XM_011510119 XP_011508421 NM_001764 NP_001755 |
Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts. |
Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
Top Pathways | Hematopoietic cell lineage |
CD1B CRISPR/Cas9 KO Plasmid (h) - sc-417718 from Santa Cruz Biotechnology
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CD1B HDR Plasmid (h) - sc-417718-HDR from Santa Cruz Biotechnology
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CD1B Double Nickase Plasmid (h) - sc-417718-NIC from Santa Cruz Biotechnology
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CD1B Double Nickase Plasmid (h2) - sc-417718-NIC-2 from Santa Cruz Biotechnology
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CD1B CRISPR Activation Plasmid (h) - sc-417718-ACT from Santa Cruz Biotechnology
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CD1B CRISPR Activation Plasmid (h2) - sc-417718-ACT-2 from Santa Cruz Biotechnology
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CD1B Lentiviral Activation Particles (h) - sc-417718-LAC from Santa Cruz Biotechnology
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CD1B Lentiviral Activation Particles (h2) - sc-417718-LAC-2 from Santa Cruz Biotechnology
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CD1B siRNA (h) - sc-42745 from Santa Cruz Biotechnology
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CD1B shRNA Plasmid (h) - sc-42745-SH from Santa Cruz Biotechnology
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CD1B shRNA (h) Lentiviral Particles - sc-42745-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU029431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5690 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5690 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01807 from Sigma-Aldrich
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CD1B siRNA (Human) - CRH0639 from Cohesion Biosciences
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CD1B - MBS8240374 from MyBioSource
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shRNA set against Human CD1B (NM_001764.2) - SHH258585 from Creative biogene
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CD1B shRNA Plasmid (Human) - CHH0639 from Cohesion Biosciences
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CD1B miRNA 3'UTR clone - MiUTR1H-01845 from Creative biogene
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