| Gene Symbol |
FAM129A
|
| Entrez Gene |
116496
|
| Alt Symbol |
C1orf24, GIG39, NIBAN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
family with sequence similarity 129, member A
|
| Other Description |
cell growth-inhibiting gene 39 protein|protein Niban
|
| Swissprots |
Q8TEI5 Q5TEM8 Q9BZQ8 Q9HCB9 Q9H9Y8 Q9H593 Q2TTR2
|
| Accessions |
CAY55964 EAW91184 EAW91185 Q9BZQ8 AB050477 BAB17230 AF288391 AAG60611 AK022527 BAB14079 AK074139 BAB84965 AK095547 AK127373 AK310557 AK311019 AL137572 AY550972 AAT52218 BC018532 BC030531 AAH30531 DC346827 XM_011509140 XP_011507442 XM_011509141 XP_011507443 NM_052966 NP_443198
|
| Function |
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16949643}.
|
| Tissue Specificity |
Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney. {ECO:0000269|PubMed:11011112, ECO:0000269|PubMed:16949643}.
|