Gene Symbol | FAM129A |
---|---|
Entrez Gene | 116496 |
Alt Symbol | C1orf24, GIG39, NIBAN |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 129, member A |
Other Description | cell growth-inhibiting gene 39 protein|protein Niban |
Swissprots | Q8TEI5 Q5TEM8 Q9BZQ8 Q9HCB9 Q9H9Y8 Q9H593 Q2TTR2 |
Accessions | CAY55964 EAW91184 EAW91185 Q9BZQ8 AB050477 BAB17230 AF288391 AAG60611 AK022527 BAB14079 AK074139 BAB84965 AK095547 AK127373 AK310557 AK311019 AL137572 AY550972 AAT52218 BC018532 BC030531 AAH30531 DC346827 XM_011509140 XP_011507442 XM_011509141 XP_011507443 NM_052966 NP_443198 |
Function | Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16949643}. |
Tissue Specificity | Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney. {ECO:0000269|PubMed:11011112, ECO:0000269|PubMed:16949643}. |
Niban CRISPR/Cas9 KO Plasmid (h) - sc-405758 from Santa Cruz Biotechnology
|
||||||||
Niban HDR Plasmid (h) - sc-405758-HDR from Santa Cruz Biotechnology
|
||||||||
Niban Double Nickase Plasmid (h) - sc-405758-NIC from Santa Cruz Biotechnology
|
||||||||
Niban Double Nickase Plasmid (h2) - sc-405758-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Niban CRISPR Activation Plasmid (h) - sc-405758-ACT from Santa Cruz Biotechnology
|
||||||||
Niban CRISPR Activation Plasmid (h2) - sc-405758-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Niban Lentiviral Activation Particles (h) - sc-405758-LAC from Santa Cruz Biotechnology
|
||||||||
Niban Lentiviral Activation Particles (h2) - sc-405758-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Niban siRNA (h) - sc-78648 from Santa Cruz Biotechnology
|
||||||||
Niban shRNA Plasmid (h) - sc-78648-SH from Santa Cruz Biotechnology
|
||||||||
Niban shRNA (h) Lentiviral Particles - sc-78648-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU053511 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN8161 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8161 from Sigma-Aldrich
|
||||||||
FAM129A siRNA (Human) - CRJ4522 from Cohesion Biosciences
|
||||||||
FAM129A - MBS8216781 from MyBioSource
|
||||||||
Niban CRISPR/Cas9 KO Plasmid (h2) - sc-405758-KO-2 from Santa Cruz Biotechnology
|
||||||||
Niban HDR Plasmid (h2) - sc-405758-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human FAM129A (NM_052966.2) - SHH289485 from Creative biogene
|
||||||||
Human FAM129A siRNA - orb275023 from Biorbyt
|
||||||||
FAM129A shRNA Plasmid (Human) - CHJ4522 from Cohesion Biosciences
|
||||||||
FAM129A miRNA 3'UTR clone - MiUTR1H-03416 from Creative biogene
|