| Gene Symbol | ATP6V1B1 |
|---|---|
| Entrez Gene | 525 |
| Alt Symbol | ATP6B1, RTA1B, VATB, VMA2, VPP3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| Other Description | H(+)-transporting two-sector ATPase, 58kD subunit|H+-ATPase beta 1 subunit|V-ATPase B1 subunit|V-ATPase subunit B 1|V-type proton ATPase subunit B, kidney isoform|endomembrane proton pump 58 kDa subunit|vacuolar proton pump 3|vacuolar proton pump subunit B 1|vacuolar proton pump, subunit 3 |
| Swissprots | P15313 Q6P4H6 Q53FY0 |
| Accessions | AHA90857 AIU34530 EAW99790 EAW99791 P15313 AK127853 AK223151 BAD96871 AK291121 BAF83810 AK301542 BAG63039 AK313194 BAG36011 AU126647 BC035978 BC063411 AAH63411 CA944873 DA845716 M25809 AAA36498 XM_011532907 XP_011531209 NM_001692 NP_001683 |
| Function | Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Subcellular Location | Endomembrane system; Peripheral membrane protein. Note=Endomembrane. |
| Tissue Specificity | Expressed in the cochlea and endolymphatic sac. {ECO:0000269|PubMed:9916796}. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |