Gene Symbol | ATP6V1B1 |
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Entrez Gene | 525 |
Alt Symbol | ATP6B1, RTA1B, VATB, VMA2, VPP3 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
Other Description | H(+)-transporting two-sector ATPase, 58kD subunit|H+-ATPase beta 1 subunit|V-ATPase B1 subunit|V-ATPase subunit B 1|V-type proton ATPase subunit B, kidney isoform|endomembrane proton pump 58 kDa subunit|vacuolar proton pump 3|vacuolar proton pump subunit B 1|vacuolar proton pump, subunit 3 |
Swissprots | P15313 Q6P4H6 Q53FY0 |
Accessions | AHA90857 AIU34530 EAW99790 EAW99791 P15313 AK127853 AK223151 BAD96871 AK291121 BAF83810 AK301542 BAG63039 AK313194 BAG36011 AU126647 BC035978 BC063411 AAH63411 CA944873 DA845716 M25809 AAA36498 XM_011532907 XP_011531209 NM_001692 NP_001683 |
Function | Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Subcellular Location | Endomembrane system; Peripheral membrane protein. Note=Endomembrane. |
Tissue Specificity | Expressed in the cochlea and endolymphatic sac. {ECO:0000269|PubMed:9916796}. |
Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
V-ATPase B1 CRISPR/Cas9 KO Plasmid (h) - sc-400926 from Santa Cruz Biotechnology
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V-ATPase B1 HDR Plasmid (h) - sc-400926-HDR from Santa Cruz Biotechnology
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V-ATPase B1 Double Nickase Plasmid (h) - sc-400926-NIC from Santa Cruz Biotechnology
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V-ATPase B1 Double Nickase Plasmid (h2) - sc-400926-NIC-2 from Santa Cruz Biotechnology
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V-ATPase B1 CRISPR Activation Plasmid (h) - sc-400926-ACT from Santa Cruz Biotechnology
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V-ATPase B1 CRISPR Activation Plasmid (h2) - sc-400926-ACT-2 from Santa Cruz Biotechnology
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V-ATPase B1 Lentiviral Activation Particles (h) - sc-400926-LAC from Santa Cruz Biotechnology
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V-ATPase B1 Lentiviral Activation Particles (h2) - sc-400926-LAC-2 from Santa Cruz Biotechnology
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V-ATPase B1 siRNA (h) - sc-36787 from Santa Cruz Biotechnology
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V-ATPase B1 shRNA Plasmid (h) - sc-36787-SH from Santa Cruz Biotechnology
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V-ATPase B1 shRNA (h) Lentiviral Particles - sc-36787-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU017741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3727 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3727 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02658 from Sigma-Aldrich
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ATP6V1B1 siRNA (Human) - CRH0363 from Cohesion Biosciences
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ATP6V1B1 RNAi - H00000525-R02 from Novus Biologicals
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ATP6V1B1 - MBS8219310 from MyBioSource
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shRNA set against Human ATP6V1B1 (NM_001692.3) - SHH243106 from Creative biogene
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shRNA set against Human ATP6V1B1(NM_001692.3) - SHG083673 from Creative biogene
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Human ATP6V1B1 siRNA - orb260865 from Biorbyt
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ATP6V1B1 shRNA Plasmid (Human) - CHH0363 from Cohesion Biosciences
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ATP6V1B1 miRNA 3'UTR clone - MiUTR1H-00715 from Creative biogene
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