| Gene Symbol |
ATP6V1B1
|
| Entrez Gene |
525
|
| Alt Symbol |
ATP6B1, RTA1B, VATB, VMA2, VPP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
|
| Other Description |
H(+)-transporting two-sector ATPase, 58kD subunit|H+-ATPase beta 1 subunit|V-ATPase B1 subunit|V-ATPase subunit B 1|V-type proton ATPase subunit B, kidney isoform|endomembrane proton pump 58 kDa subunit|vacuolar proton pump 3|vacuolar proton pump subunit B 1|vacuolar proton pump, subunit 3
|
| Swissprots |
P15313 Q6P4H6 Q53FY0
|
| Accessions |
AHA90857 AIU34530 EAW99790 EAW99791 P15313 AK127853 AK223151 BAD96871 AK291121 BAF83810 AK301542 BAG63039 AK313194 BAG36011 AU126647 BC035978 BC063411 AAH63411 CA944873 DA845716 M25809 AAA36498 XM_011532907 XP_011531209 NM_001692 NP_001683
|
| Function |
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
|
| Subcellular Location |
Endomembrane system; Peripheral membrane protein. Note=Endomembrane.
|
| Tissue Specificity |
Expressed in the cochlea and endolymphatic sac. {ECO:0000269|PubMed:9916796}.
|
| Top Pathways |
Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis
|
![Western Blot: ATP6V1B1 Overexpression Lysate (Adult Normal) [NBL1-07838] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATP6V1B1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5322_ATP6V1B1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07838-img0002.jpg)