HSPA5

Gene Symbol	HSPA5
Entrez Gene	3309
Alt Symbol	BIP, GRP78, HEL-S-89n, MIF2
Species	Human
Gene Type	protein-coding
Description	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Other Description	78 kDa glucose-regulated protein|endoplasmic reticulum lumenal Ca(2+)-binding protein grp78|epididymis secretory sperm binding protein Li 89n|immunoglobulin heavy chain-binding protein
Swissprots	Q9UK02 Q9NPF1 Q2EF78 P11021 B0QZ61
Accessions	AAA52614 ABD04090 CAA42595 CAK18759 EAW87620 EAW87621 P11021 AA433933 AF188611 AAF13605 AF216292 AAF42836 AJ271729 CAB71335 AK129617 AK293604 BAG57068 BC020235 AAH20235 DA549454 DQ892173 ABM83099 DQ895368 ABM86294 EU794617 ACJ13671 X87949 CAA61201 NM_005347 NP_005338
Function	Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. {ECO:0000269|PubMed:2294010, ECO:0000269|PubMed:23769672, ECO:0000269|PubMed:23990668}.
Subcellular Location	Endoplasmic reticulum lumen. Melanosome. Cytoplasm {ECO:0000250}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Protein export, Prion diseases, Protein processing in endoplasmic reticulum, Thyroid hormone synthesis, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human GRP78 BiP full length protein - ab78432 from Abcam Category Protein Prices $239.00 Sizes 50 µg Source E. coli Species Human

Chinese Hamster GRP78 BiP full length protein - ab92363 from Abcam Category Protein Prices $188.00 Sizes 50 µg Source E. coli Species Hamster

GRP78 BiP peptide - ab176142 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

GRP78 BiP peptide - ab176143 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human GRP78 BiP full length protein - ab167897 from Abcam Category Protein Source E. coli Species Human

Human GRP78 BiP protein fragment - ab79139 from Abcam Category Protein Source E. coli Species Human

Mouse GRP78 BiP peptide - ab22410 from Abcam Category Peptide

HSPA5 / GRP78 / BiP Antibody Blocking Peptide - LS-E7706 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSPA5 / GRP78 / BiP Antibody Blocking Peptide - LS-E7707 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GRP78/HSPA5 Protein - H00003309-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRP78/HSPA5 Blocking Peptide - NBP1-06274PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

GRP78/HSPA5 Blocking Peptide - NBP1-06277PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

GRP78/HSPA5 Partial Recombinant Protein - H00003309-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human GRP78/HSPA5 Protein - NBC1-18378 from Novus Biologicals Category Protein Prices $369.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human GRP78/HSPA5 Protein - NBP2-23104 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human GRP78/HSPA5 Protein - NBP1-50908 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source Baculovirus Species Human

HSPA5-Antibody-Center-Blocking-Peptide - BP5041c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSPA5-Antibody-C-term-Blocking-peptide - BP5041b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSPA5 Protein (OPPA02589) - OPPA02589 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source His-5 Cells

Human HSPA5 protein - orb168525 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human HSPA5 protein - orb168526 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source Hi-5 Cells.

Human heat shock 70kDa protein 5 protein - orb81502 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human HSPA5 (19-654) protein - orb191213 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

Human GRP78 protein - orb245222 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BIP protein - 30R-1212 from Fitzgerald Category Protein Prices $395.00 Sizes 100 µg Source E.coli

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