| Gene Symbol |
CATSPERD
|
| Entrez Gene |
257062
|
| Alt Symbol |
TMEM146
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
catsper channel auxiliary subunit delta
|
| Other Description |
catSper-delta|catSperdelta|cation channel sperm-associated protein subunit delta|transmembrane protein 146
|
| Swissprots |
Q86XM0 Q6ZRP1
|
| Accessions |
EAW69148 EAW69149 EAW69150 Q86XM0 AK128088 BC031233 AAH31233 BC043005 AAH43005 XM_011527885 XP_011526187 XM_011527886 XP_011526188 XM_011527887 XP_011526189 XM_011527888 XP_011526190 XM_011527889 XP_011526191 XM_011527890 XP_011526192 XM_011527891 XP_011526193 XM_011527892 XP_011526194 NM_152784 NP_689997
|
| Function |
Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell projection, cilium, flagellum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000250}.
|
![Western Blot: TMEM146 Overexpression Lysate (Adult Normal) [NBP2-05308] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEM146.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10435_TMEM146%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05308-img0001.jpg)