Gene Symbol | CATSPERD |
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Entrez Gene | 257062 |
Alt Symbol | TMEM146 |
Species | Human |
Gene Type | protein-coding |
Description | catsper channel auxiliary subunit delta |
Other Description | catSper-delta|catSperdelta|cation channel sperm-associated protein subunit delta|transmembrane protein 146 |
Swissprots | Q86XM0 Q6ZRP1 |
Accessions | EAW69148 EAW69149 EAW69150 Q86XM0 AK128088 BC031233 AAH31233 BC043005 AAH43005 XM_011527885 XP_011526187 XM_011527886 XP_011526188 XM_011527887 XP_011526189 XM_011527888 XP_011526190 XM_011527889 XP_011526191 XM_011527890 XP_011526192 XM_011527891 XP_011526193 XM_011527892 XP_011526194 NM_152784 NP_689997 |
Function | Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CATSPER1 stability before intraflagellar transport and/or incorporation of the CatSper complex channel into the flagellar membrane (By similarity). {ECO:0000250}. |
Subcellular Location | Cell projection, cilium, flagellum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000250}. |
CatSperδ CRISPR/Cas9 KO Plasmid (h) - sc-408427 from Santa Cruz Biotechnology
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CatSperδ HDR Plasmid (h) - sc-408427-HDR from Santa Cruz Biotechnology
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CatSperδ Double Nickase Plasmid (h) - sc-408427-NIC from Santa Cruz Biotechnology
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CatSperδ Double Nickase Plasmid (h2) - sc-408427-NIC-2 from Santa Cruz Biotechnology
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CatSperδ CRISPR Activation Plasmid (h) - sc-408427-ACT from Santa Cruz Biotechnology
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CatSperδ CRISPR Activation Plasmid (h2) - sc-408427-ACT-2 from Santa Cruz Biotechnology
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CatSperδ Lentiviral Activation Particles (h) - sc-408427-LAC from Santa Cruz Biotechnology
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CatSperδ Lentiviral Activation Particles (h2) - sc-408427-LAC-2 from Santa Cruz Biotechnology
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CatSperδ siRNA (h) - sc-97656 from Santa Cruz Biotechnology
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CatSperδ shRNA Plasmid (h) - sc-97656-SH from Santa Cruz Biotechnology
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CatSperδ shRNA (h) Lentiviral Particles - sc-97656-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU050811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21512 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21512 from Sigma-Aldrich
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CATSPERD siRNA (Human) - CRJ6777 from Cohesion Biosciences
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CATSPERD - MBS8225826 from MyBioSource
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shRNA set against Human TMEM146 (NM_152784.3) - SHH429212 from Creative biogene
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shRNA set against Human TMEM146(NM_152784.3) - SHL042678 from Creative biogene
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Human CATSPERD siRNA - orb277278 from Biorbyt
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CATSPERD shRNA Plasmid (Human) - CHJ6777 from Cohesion Biosciences
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CATSPERD miRNA 3'UTR clone - MiUTR1H-10499 from Creative biogene
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