| Gene Symbol |
TCEB3
|
| Entrez Gene |
6924
|
| Alt Symbol |
EloA, SIII, SIII p110, TCEB3A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
|
| Other Description |
RNA polymerase II transcription factor SIII subunit A1|elongin 110 kDa subunit|elongin-A|transcription elongation factor B alpha subunit|transcription elongation factor B polypeptide 3
|
| Swissprots |
Q14241 B2R7Q8 Q8IXH1
|
| Accessions |
EAW95070 EAW95071 Q14241 AF070554 AF116729 AAO15305 AK096079 AK310229 AK313079 BAG35905 AW451236 BC002883 AAH02883 BC019949 BC020448 DB461774 DQ893026 ABM83952 DQ896270 ABM87269 L47345 AAA75492 NM_003198 NP_003189
|
| Function |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|