Gene Symbol | TCEB3 |
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Entrez Gene | 6924 |
Alt Symbol | EloA, SIII, SIII p110, TCEB3A |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
Other Description | RNA polymerase II transcription factor SIII subunit A1|elongin 110 kDa subunit|elongin-A|transcription elongation factor B alpha subunit|transcription elongation factor B polypeptide 3 |
Swissprots | Q14241 B2R7Q8 Q8IXH1 |
Accessions | EAW95070 EAW95071 Q14241 AF070554 AF116729 AAO15305 AK096079 AK310229 AK313079 BAG35905 AW451236 BC002883 AAH02883 BC019949 BC020448 DB461774 DQ893026 ABM83952 DQ896270 ABM87269 L47345 AAA75492 NM_003198 NP_003189 |
Function | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). |
Subcellular Location | Nucleus {ECO:0000305}. |
Elongin A CRISPR/Cas9 KO Plasmid (h) - sc-404668 from Santa Cruz Biotechnology
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Elongin A HDR Plasmid (h) - sc-404668-HDR from Santa Cruz Biotechnology
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Elongin A Double Nickase Plasmid (h) - sc-404668-NIC from Santa Cruz Biotechnology
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Elongin A Double Nickase Plasmid (h2) - sc-404668-NIC-2 from Santa Cruz Biotechnology
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Elongin A CRISPR Activation Plasmid (h) - sc-404668-ACT from Santa Cruz Biotechnology
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Elongin A CRISPR Activation Plasmid (h2) - sc-404668-ACT-2 from Santa Cruz Biotechnology
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Elongin A Lentiviral Activation Particles (h) - sc-404668-LAC from Santa Cruz Biotechnology
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Elongin A Lentiviral Activation Particles (h2) - sc-404668-LAC-2 from Santa Cruz Biotechnology
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Elongin A siRNA (h) - sc-35292 from Santa Cruz Biotechnology
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Elongin A shRNA Plasmid (h) - sc-35292-SH from Santa Cruz Biotechnology
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Elongin A shRNA (h) Lentiviral Particles - sc-35292-V from Santa Cruz Biotechnology
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Elongin A RNAi - H00006924-R01 from Novus Biologicals
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MISSION® esiRNA - EHU001411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21133 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21133 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02084 from Sigma-Aldrich
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TCEB3 siRNA (Human) - CRH4746 from Cohesion Biosciences
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TCEB3 - MBS8216301 from MyBioSource
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Elongin A CRISPR/Cas9 KO Plasmid (h2) - sc-404668-KO-2 from Santa Cruz Biotechnology
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Elongin A HDR Plasmid (h2) - sc-404668-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TCEB3 (NM_003198.2) - SHH424692 from Creative biogene
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Human TCEB3 siRNA - orb265248 from Biorbyt
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TCEB3 shRNA Plasmid (Human) - CHH4746 from Cohesion Biosciences
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TCEB3 miRNA 3'UTR clone - MiUTR4H-TG08841 from Creative biogene
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