| Gene Symbol |
CCR8
|
| Entrez Gene |
1237
|
| Alt Symbol |
CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-C motif) receptor 8
|
| Other Description |
C-C chemokine receptor type 8|CC chemokine receptor 8|CC chemokine receptor CHEMR1|CC-chemokine receptor chemr1|chemokine (C-C) receptor 8|chemokine (C-C) receptor-like 2|chemokine receptor-like 1
|
| Swissprots |
B2RC64 Q3KNQ8 Q9BYX5 Q3KNR3 P51685
|
| Accessions |
AAB05542 AAB61962 AAK08628 CAA69712 CAB02142 EAW64577 P51685 AF005210 AAB62547 AK314957 BAG37461 BC069067 AAH69067 BC074743 AAH74743 BC107152 AAI07153 BC107159 AAI07160 D49919 BAA23387 NM_005201 NP_005192
|
| Function |
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. {ECO:0000269|PubMed:10540332, ECO:0000269|PubMed:9207005, ECO:0000269|PubMed:9469461, ECO:0000269|PubMed:9521068}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Viral carcinogenesis
|