CACNA1S

Gene Symbol	CACNA1S
Entrez Gene	779
Alt Symbol	CACNL1A3, CCHL1A3, Cav1.1, HOKPP, HOKPP1, MHS5, TTPP1, hypoPP
Species	Human
Gene Type	protein-coding
Description	calcium channel, voltage-dependent, L type, alpha 1S subunit
Other Description	calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis)|dihydropyridine receptor|dihydropyridine-sensitive L-type calcium channel alpha-1 subunit|voltage-dependent L-type calcium channel subunit alpha-1S|voltage-gated calcium channel subunit alpha Cav1.1
Swissprots	Q13934 A4IF51 Q12896 B1ALM2 Q13698
Accessions	AAB37235 EAW91333 EAW91334 EAW91335 Q13698 BC133671 AAI33672 L33798 AAA51902 U09784 AAA20531 U14413 AAC50397 U18986 AAC50398 XM_005245478 XP_005245535 NM_000069 NP_000060
Function	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Skeletal muscle specific.
Top Pathways	Alzheimer's disease, Arrhythmogenic right ventricular cardiomyopathy (ARVC), cAMP signaling pathway, MAPK signaling pathway, Calcium signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse CACNA1S / Cav1.1 ELISA Kit (Sandwich ELISA) - LS-F8772 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.101 ng/ml Range 0.313-20 ng/ml

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), Human, ELISA Kit - E01V0059 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Voltage dependent L type calcium channel subunit Alpha 1S (CACNA1S), ELISA Kit - MBS7242064 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit Alpha 1S (CACNA1S), ELISA Kit - MBS7232421 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7215394 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7251526 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7247437 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7224914 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7234735 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7232970 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7234784 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7213793 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S), ELISA Kit - MBS7248884 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Calcium Channel, Voltage Dependent, L-Type, Alpha 1S Subunit (CACNa1S) - SEF235Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.101ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human CACNA1S ELISA Kit - E040398 from Biobool Category ELISA Kit

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