MAP1LC3B

Gene Symbol	MAP1LC3B
Entrez Gene	81631
Alt Symbol	ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a
Species	Human
Gene Type	protein-coding
Description	microtubule-associated protein 1 light chain 3 beta
Other Description	MAP1 light chain 3-like protein 2|MAP1A/MAP1B LC3 B|MAP1A/MAP1B light chain 3 B|autophagy-related ubiquitin-like modifier LC3 B|microtubule-associated proteins 1A/1B light chain 3B
Swissprots	Q6NW02 Q9GZQ8
Accessions	EAW95392 EAW95393 EAW95394 EAW95395 EAW95396 EAW95397 EAW95398 EAW95399 Q9GZQ8 AF087871 AAM10499 AF183417 AAG09686 AF303888 AAG23182 AK024571 AK025556 BAB15169 AK290956 BAF83645 AK310224 AK310335 AL834298 CAD38970 AM393561 CAL38438 BC018634 AAH18634 BC041874 AAH41874 BC045759 AAH45759 BC048009 BC067797 AAH67797 BG771621 DA577457 DB055844 DQ893152 ABM84078 DQ896448 ABM87447 JN663879 AEZ06292 NM_022818 NP_073729
Function	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. {ECO:0000269|PubMed:20418806, ECO:0000269|PubMed:23209295, ECO:0000269|PubMed:24089205}.
Subcellular Location	Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes. Localizes also to discrete punctae along the ciliary axoneme (By similarity). {ECO:0000250}.
Tissue Specificity	Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. {ECO:0000269|PubMed:12740394}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LC3B full length protein - ab157023 from Abcam Category Protein Source E. coli Species Human

Human LC3B full length protein - ab103506 from Abcam Category Protein Source E. coli Species Human

Human LC3B peptide - ab87823 from Abcam Category Peptide

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E372 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E1711 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5542 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5507 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5508 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5510 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5509 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E5515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E7410 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E7475 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E7479 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP1LC3B / LC3B Antibody Blocking Peptide - LS-E7483 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LC3B Blocking Peptide - NB100-2220PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg

LC3B/MAP1LC3B Partial Recombinant Protein - H00081631-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

LC3B/MAP1LC3B Recombinant Protein - H00081631-P01 from Novus Biologicals Category Protein Prices $539.00 Sizes 25 µg Species Human

Recombinant Human LC3B Protein - NBP1-50960 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

LC3B/MAP1LC3B Peptide - P1662 from Novus Biologicals Category Peptide Species Human

APG8abMAP1LC3AB-Antibody-Blocking-peptide - BP10648a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APG8bMAP1LC3B-Antibody-N-term-T29-Blocking-peptide - BP12484a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APG8b-Antibody-N-term-T29-Blocking-peptide - BP14329a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cleaved-LC3B-Antibody-Blocking-peptide - BP1806a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LC3-Antibody-APG8ab-Blocking-Peptide - BP1803a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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