Gene Symbol |
SPRR2B
|
Entrez Gene |
6701
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
small proline-rich protein 2B
|
Other Description |
SPR-2B
|
Swissprots |
Q5T528 P35325
|
Accessions |
AAA60576 AAK70940 CAP07544 CAP11512 CAR97127 CAT82408 EAW53345 P35325 BC148719 AAI48720 BF090370 CA311074 NM_001017418 NP_001017418
|
Function |
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
|