Gene Symbol | SPRR2B |
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Entrez Gene | 6701 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | small proline-rich protein 2B |
Other Description | SPR-2B |
Swissprots | Q5T528 P35325 |
Accessions | AAA60576 AAK70940 CAP07544 CAP11512 CAR97127 CAT82408 EAW53345 P35325 BC148719 AAI48720 BF090370 CA311074 NM_001017418 NP_001017418 |
Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea. |
SPRR2B CRISPR/Cas9 KO Plasmid (h) - sc-417928 from Santa Cruz Biotechnology
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SPRR2B HDR Plasmid (h) - sc-417928-HDR from Santa Cruz Biotechnology
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SPRR2B Double Nickase Plasmid (h) - sc-417928-NIC from Santa Cruz Biotechnology
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SPRR2B Double Nickase Plasmid (h2) - sc-417928-NIC-2 from Santa Cruz Biotechnology
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SPRR2B CRISPR Activation Plasmid (h) - sc-417928-ACT from Santa Cruz Biotechnology
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SPRR2B CRISPR Activation Plasmid (h2) - sc-417928-ACT-2 from Santa Cruz Biotechnology
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SPRR2B Lentiviral Activation Particles (h) - sc-417928-LAC from Santa Cruz Biotechnology
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SPRR2B Lentiviral Activation Particles (h2) - sc-417928-LAC-2 from Santa Cruz Biotechnology
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SPRR2B siRNA (h) - sc-88442 from Santa Cruz Biotechnology
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SPRR2B shRNA Plasmid (h) - sc-88442-SH from Santa Cruz Biotechnology
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SPRR2B shRNA (h) Lentiviral Particles - sc-88442-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU127231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20521 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02904 from Sigma-Aldrich
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SPRR2B siRNA (Human) - CRH4571 from Cohesion Biosciences
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SPRR2B - MBS8233330 from MyBioSource
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shRNA set against Human SPRR2B (NM_001017418.1) - SHH417268 from Creative biogene
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shRNA set against Human SPRR2B(NM_001017418.1) - SHL030828 from Creative biogene
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Human SPRR2B siRNA - orb265073 from Biorbyt
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SPRR2B shRNA Plasmid (Human) - CHH4571 from Cohesion Biosciences
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SPRR2B miRNA 3'UTR clone - MiUTR1H-09872 from Creative biogene
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