| Gene Symbol |
GPR18
|
| Entrez Gene |
2841
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 18
|
| Other Description |
N-arachidonyl glycine receptor|NAGly receptor
|
| Swissprots |
Q96HI6 Q14330 Q9H2L2 Q6GTM3
|
| Accessions |
AAB65819 EAX09017 Q14330 AA825595 AF261135 AAG44671 AF339781 BC008569 AAH08569 BC050646 AAH50646 BC066927 AAH66927 BI770379 BT009907 AAP88909 JQ308176 AFF59486 XM_006719946 XP_006720009 XM_011521078 XP_011519380 XM_011521079 XP_011519381 XM_011521080 XP_011519382 XM_011521081 XP_011519383 NM_001098200 NP_001091670 NM_005292 NP_005283
|
| Function |
Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. {ECO:0000269|PubMed:16844083}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells. {ECO:0000269|PubMed:16844083}.
|
![Western Blot: GPR18 Overexpression Lysate (Adult Normal) [NBP2-10475] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR18.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2270_GPR18%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10475-img0001.jpg)
![Western Blot: GPR18 Overexpression Lysate (Adult Normal) [NBP2-10926] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR18.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9574_GPR18%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10926-img0001.jpg)