Gene Symbol | GPR18 |
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Entrez Gene | 2841 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 18 |
Other Description | N-arachidonyl glycine receptor|NAGly receptor |
Swissprots | Q96HI6 Q14330 Q9H2L2 Q6GTM3 |
Accessions | AAB65819 EAX09017 Q14330 AA825595 AF261135 AAG44671 AF339781 BC008569 AAH08569 BC050646 AAH50646 BC066927 AAH66927 BI770379 BT009907 AAP88909 JQ308176 AFF59486 XM_006719946 XP_006720009 XM_011521078 XP_011519380 XM_011521079 XP_011519381 XM_011521080 XP_011519382 XM_011521081 XP_011519383 NM_001098200 NP_001091670 NM_005292 NP_005283 |
Function | Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. {ECO:0000269|PubMed:16844083}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells. {ECO:0000269|PubMed:16844083}. |
GPR18 CRISPR/Cas9 KO Plasmid (h) - sc-407609 from Santa Cruz Biotechnology
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GPR18 HDR Plasmid (h) - sc-407609-HDR from Santa Cruz Biotechnology
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GPR18 Double Nickase Plasmid (h) - sc-407609-NIC from Santa Cruz Biotechnology
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GPR18 Double Nickase Plasmid (h2) - sc-407609-NIC-2 from Santa Cruz Biotechnology
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GPR18 CRISPR Activation Plasmid (h) - sc-407609-ACT from Santa Cruz Biotechnology
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GPR18 CRISPR Activation Plasmid (h2) - sc-407609-ACT-2 from Santa Cruz Biotechnology
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GPR18 Lentiviral Activation Particles (h) - sc-407609-LAC from Santa Cruz Biotechnology
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GPR18 Lentiviral Activation Particles (h2) - sc-407609-LAC-2 from Santa Cruz Biotechnology
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GPR18 siRNA (h) - sc-75170 from Santa Cruz Biotechnology
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GPR18 shRNA Plasmid (h) - sc-75170-SH from Santa Cruz Biotechnology
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GPR18 shRNA (h) Lentiviral Particles - sc-75170-V from Santa Cruz Biotechnology
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GPR18 RNAi - H00002841-R02 from Novus Biologicals
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MISSION® esiRNA - EHU090431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9587 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9587 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00400 from Sigma-Aldrich
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GPR18 siRNA (Human) - CRH1904 from Cohesion Biosciences
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GPR18 - MBS8222656 from MyBioSource
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shRNA set against Human GPR18 (NM_005292.3) - SHH306618 from Creative biogene
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shRNA set against Human GPR18(NM_005292.3) - SHH099317 from Creative biogene
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Human GPR18 siRNA - orb262406 from Biorbyt
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GPR18 shRNA Plasmid (Human) - CHH1904 from Cohesion Biosciences
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GPR18 miRNA 3'UTR clone - MiUTR1H-04205 from Creative biogene
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GPR18 miRNA 3'UTR clone - MiUTR3H-04619 from Creative biogene
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