| Gene Symbol |
RPH3AL
|
| Entrez Gene |
9501
|
| Alt Symbol |
NOC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
rabphilin 3A-like (without C2 domains)
|
| Other Description |
no C2 domains protein|rab effector Noc2
|
| Swissprots |
Q9BSB3 Q9UNE2 D3DTG7
|
| Accessions |
EAW90669 EAW90670 EAW90671 EAW90672 Q9UNE2 AF129812 AAD45582 AK000469 BAA91186 AK291950 BAF84639 BC005153 AAH05153 BC093776 AAH93776 BC113413 AAI13414 BC143311 BF507559 BP275333 BU197069 BU568991 DA378956 HQ258174 ADR82928 XM_011535364 XP_011533666 XM_011535365 XP_011533667 XM_011535366 XP_011533668 XM_011535367 XP_011533669 XM_011535368 XP_011533670 XM_011535369 XP_011533671 XM_011546997 XP_011545299 XM_011546998 XP_011545300 XM_011546999 XP_011545301 XM_011547000 XP_011545302 XM_011547001 XP_011545303 XM_011547002 XP_011545304 XM_011547003 XP_011545305 XR_942191 XR_952112 NM_001190411 NP_001177340 NM_001190412 NP_001177341 NM_001190413 NP_001177342 NM_006987 NP_008918
|
| Function |
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. {ECO:0000250, ECO:0000269|PubMed:15003533}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15003533}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:15003533}. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
|
| Tissue Specificity |
Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells. {ECO:0000269|PubMed:10395805, ECO:0000269|PubMed:15003533}.
|