THRA

Gene Symbol THRA
Entrez Gene 7067
Alt Symbol AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1
Species Human
Gene Type protein-coding
Description thyroid hormone receptor, alpha
Other Description EAR-7|ERBA-related 7|V-erbA-related protein 7|c-erbA-alpha|nuclear receptor subfamily 1 group A member 1|thyroid hormone receptor alpha|thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)|thyroid normone nuclear receptor alpha variant 1|triiodothyronine receptor
Swissprots A8K3B5 Q96H73 Q8N6A1 P10827 P21205
Accessions AAA66021 CAA38899 CAB57886 EAW60632 EAW60633 EAW60634 P10827 AB209346 BAD92583 AB307686 BAH02277 AF522368 AAM77692 AK290071 BAF82760 AK290530 BAF83219 AK311344 BC000261 AAH00261 BC002728 AAH02728 BC008851 AAH08851 BC035137 AAH35137 BQ224043 CR541915 CAG46713 DQ892512 ABM83438 DQ895726 ABM86652 HQ692859 ADZ17370 J03239 AAA61176 M24899 AAA35783 M24900 AAA52333 X55005 CAA38749 Y00479 CAA68539 NM_001190918 NP_001177847 NM_001190919 NP_001177848 NM_003250 NP_003241 NM_199334 NP_955366
Function Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. {ECO:0000269|PubMed:12699376, ECO:0000269|PubMed:14673100, ECO:0000269|PubMed:18237438, ECO:0000269|PubMed:19926848}.
Subcellular Location Nucleus.
Top Pathways Neuroactive ligand-receptor interaction

TRα (T-17) - sc-10819 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRα1/α2 (2103) - sc-56873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
TRα1/α2 (2103): sc-56873. Western blot analysis of TRα1/α2 expression in Hep G2 nuclear extract.

TRα1/α2 (3C185) - sc-73213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
TRα1/α2 (3C185): sc-73213. Western blot analysis of TRα1/α2 expression in Hep G2 nuclear extract.

TRα1/α2 (948C3a) - sc-130021 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TRα1/α2 (948C3a): sc-130021. Western blot analysis of human recombinant TRα1/α2 fusion protein.

TRα2 (1330) - sc-56875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
TRα2 (1330): sc-56875. Western blot analysis of TRα2 expression in C32 (A) and SK-N-MC (B) nuclear extracts.

TRα/β (FL-408) - sc-772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRα/β (FL-408): sc-772. Western blot analysis of TRα/β expression in C32 nuclear extract (A) and C32 whole cell lysate (B).

TRα1/β1 (C1) - sc-739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of TRβ1 expression in ZL (293 cells stably expressing TRβ1) whole cell lysate. Antibodies tested include TRα1/β1 (C1): sc-739 (A) and TRα1/β1 (C4): sc-740 (B). Kindly provided by Sheue-Yann Cheng at the National Institutes of Health.

TRα1/β1 (C4) - sc-740 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TRα1/β1 (C4): sc-740. Western blot analysis of in vitro synthesized human TRβ1 (A-C) and TRα1 (D-F) prepared from TNT T7 programmed lysates. [1µL (A,D), 3µL (B,E), and 6µL (C,F)]

Anti-Thyroid Hormone Receptor alpha 1+2 antibody - ab15543 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted - ab15544 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal

Anti-Thyroid Hormone Receptor alpha 2 antibody - ab97887 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] - ab30582 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1330
Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582) at 1/1000 dilution + human hippocampal lysate

Anti-Thyroid Hormone Receptor alpha antibody - ab53729 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab53729 at 1/50 dilution staining Thyroid Hormone Receptor alpha in human colon carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-Thyroid Hormone Receptor alpha antibody - ab172214 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-Thyroid Hormone Receptor alpha antibody (ab172214) at 1/500 dilutionLane 1 : Thyroid Hormone Receptor alpha transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-Thyroid Hormone Receptor alpha antibody [EPR7862] - ab179438 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7862
All lanes : Anti-Thyroid Hormone Receptor alpha antibody [EPR7862] (ab179438) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : Molt-4 cell lysateLane 3 : MCF-7 cell lysateLysates/proteins at 10 µg per lane.

Anti-Thyroid Hormone Receptor antibody - ab63962 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Thyroid Hormone Receptor antibody (ab63962) at 0.5 µg/ml + Human Bone Marrow lysate at 35 µg

Anti-Thyroid Hormone Receptor antibody - ab103815 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Thyroid Hormone Receptor antibody (ab103815) at 1/500 dilution + HepG2 cell lysate at 50 µg

Anti-Thyroid Hormone Receptor antibody [C3] - ChIP Grade - ab2743 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone C3
Immunocytochemistry/Immunofluorescence analysis of Thyroid Hormone Receptor in HeLa cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with ab2743 (1:20) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Thyroid Hormone Receptor staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

Anti-THRA / THR Alpha Antibody (aa1-220, clone 7G2) - LS-C339479 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7G2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY THRA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA.

Anti-THRA / THR Alpha Antibody (aa1-220, clone 2A2) - LS-C339494 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A2
IHC of paraffin-embedded Human Ovary tissue using anti-THRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-THRA / THR Alpha Antibody (aa1-220, clone 6B7) - LS-C340644 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6B7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY THRA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA.

Anti-THRA / THR Alpha Antibody (aa1-220, clone 3E10) - LS-C339495 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E10
IHC of paraffin-embedded Human Ovary tissue using anti-THRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-THRA / THR Alpha Antibody (aa1-220, clone 5A8) - LS-C339446 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A8
HEK293T cells were transfected with the pCMV6-AC-GFP control (Left lane) or pCMV6-AC-GFP THRA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-THRA.

Anti-THRA / THR Alpha Antibody (clone 948C3a) - LS-C342655 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 948C3a
Western blot analysis of immunized recombinant protein, using anti-THRA monoclonal antibody.

Anti-THRA / THR Alpha Antibody (Ligand-binding Domain) IHC-plus™ - LS-A6196 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-THRA antibody LS-A6196 IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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