| Gene Symbol |
TMEM55A
|
| Entrez Gene |
55529
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 55A
|
| Other Description |
PtdIns-4,5-P(2) 4-phosphatase type II|ptdIns-4,5-P2 4-Ptase II|type 2 PtdIns-4,5-P2 4-Ptase|type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase|type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase
|
| Swissprots |
Q68CU2 B2R9H4 Q8N4L2
|
| Accessions |
EAW91672 EAW91673 Q8N4L2 AK313783 BAG36521 AX775961 CAE11680 BC033892 AAH33892 CR749733 CAH18492 DA171968 HQ447349 ADQ31835 XM_011517152 XP_011515454 NM_018710 NP_061180
|
| Function |
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate. {ECO:0000269|PubMed:16365287}.
|
| Subcellular Location |
Late endosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}. Lysosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:16365287}.
|
![Western Blot: TMEM55A Overexpression Lysate (Adult Normal) [NBL1-17090] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEM55A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7286_TMEM55A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17090-img0002.jpg)