Gene Symbol | TMEM55A |
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Entrez Gene | 55529 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 55A |
Other Description | PtdIns-4,5-P(2) 4-phosphatase type II|ptdIns-4,5-P2 4-Ptase II|type 2 PtdIns-4,5-P2 4-Ptase|type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase|type II phosphatidylinositol 4,5-bisphosphate 4-phosphatase |
Swissprots | Q68CU2 B2R9H4 Q8N4L2 |
Accessions | EAW91672 EAW91673 Q8N4L2 AK313783 BAG36521 AX775961 CAE11680 BC033892 AAH33892 CR749733 CAH18492 DA171968 HQ447349 ADQ31835 XM_011517152 XP_011515454 NM_018710 NP_061180 |
Function | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate. {ECO:0000269|PubMed:16365287}. |
Subcellular Location | Late endosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}. Lysosome membrane {ECO:0000269|PubMed:16365287}; Multi-pass membrane protein {ECO:0000269|PubMed:16365287}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:16365287}. |
TMEM55A CRISPR/Cas9 KO Plasmid (h) - sc-410009 from Santa Cruz Biotechnology
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TMEM55A HDR Plasmid (h) - sc-410009-HDR from Santa Cruz Biotechnology
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TMEM55A Double Nickase Plasmid (h) - sc-410009-NIC from Santa Cruz Biotechnology
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TMEM55A Double Nickase Plasmid (h2) - sc-410009-NIC-2 from Santa Cruz Biotechnology
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TMEM55A CRISPR Activation Plasmid (h) - sc-410009-ACT from Santa Cruz Biotechnology
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TMEM55A CRISPR Activation Plasmid (h2) - sc-410009-ACT-2 from Santa Cruz Biotechnology
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TMEM55A Lentiviral Activation Particles (h) - sc-410009-LAC from Santa Cruz Biotechnology
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TMEM55A Lentiviral Activation Particles (h2) - sc-410009-LAC-2 from Santa Cruz Biotechnology
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TMEM55A siRNA (h) - sc-77757 from Santa Cruz Biotechnology
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TMEM55A shRNA Plasmid (h) - sc-77757-SH from Santa Cruz Biotechnology
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TMEM55A shRNA (h) Lentiviral Particles - sc-77757-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21643 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21643 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09217 from Sigma-Aldrich
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TMEM55A siRNA (Human) - CRJ0727 from Cohesion Biosciences
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TMEM55A - MBS8201387 from MyBioSource
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shRNA set against Human TMEM55A (NM_018710.2) - SHH430708 from Creative biogene
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Human TMEM55A siRNA - orb271228 from Biorbyt
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TMEM55A shRNA Plasmid (Human) - CHJ0727 from Cohesion Biosciences
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TMEM55A miRNA 3'UTR clone - MiUTR3H-10858 from Creative biogene
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