| Gene Symbol |
AGBL3
|
| Entrez Gene |
340351
|
| Alt Symbol |
CCP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP/GTP binding protein-like 3
|
| Other Description |
ATP/GTP-binding protein-like 3|cytosolic carboxypeptidase 3
|
| Swissprots |
Q9H965 Q8NEM8 B7Z827
|
| Accessions |
EAW83837 EAW83838 Q8NEM8 AA707617 AK021841 AK023045 BAB14371 AK302827 BAH13813 AK311252 AL832281 BC030651 AAH30651 XM_011516119 XP_011514421 XM_011516120 XP_011514422 XM_011516121 XP_011514423 XM_011516122 XP_011514424 NM_178563 NP_848658
|
| Function |
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin. {ECO:0000269|PubMed:17244817}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8CDP0}.
|