| Gene Symbol |
GFRA4
|
| Entrez Gene |
64096
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GDNF family receptor alpha 4
|
| Other Description |
GDNF family receptor alpha-4|GDNF receptor alpha-4|GDNFR-alpha-4|GFR receptor alpha 4|GFR-alpha-4|persephin receptor
|
| Swissprots |
Q9GZZ7 Q9H192 Q9H191 Q5JT74
|
| Accessions |
EAX10527 EAX10528 EAX10529 Q9GZZ7 AF253318 AAG25925 AJ291673 CAC19690 AJ291674 CAC19691 AJ291675 CAC19692 BC172271 AAI72271 BC172567 AAI72567 XM_005260793 XP_005260850 NM_022139 NP_071422 NM_145762 NP_665705 NM_145763
|
| Function |
Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
|
| Subcellular Location |
Isoform GFRalpha4c: Secreted.
|
| Tissue Specificity |
Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands.
|