Gene Symbol | GFRA4 |
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Entrez Gene | 64096 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | GDNF family receptor alpha 4 |
Other Description | GDNF family receptor alpha-4|GDNF receptor alpha-4|GDNFR-alpha-4|GFR receptor alpha 4|GFR-alpha-4|persephin receptor |
Swissprots | Q9GZZ7 Q9H192 Q9H191 Q5JT74 |
Accessions | EAX10527 EAX10528 EAX10529 Q9GZZ7 AF253318 AAG25925 AJ291673 CAC19690 AJ291674 CAC19691 AJ291675 CAC19692 BC172271 AAI72271 BC172567 AAI72567 XM_005260793 XP_005260850 NM_022139 NP_071422 NM_145762 NP_665705 NM_145763 |
Function | Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. |
Subcellular Location | Isoform GFRalpha4c: Secreted. |
Tissue Specificity | Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands. |
GFRα-4 CRISPR/Cas9 KO Plasmid (h) - sc-408595 from Santa Cruz Biotechnology
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GFRα-4 HDR Plasmid (h) - sc-408595-HDR from Santa Cruz Biotechnology
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GFRα-4 Double Nickase Plasmid (h) - sc-408595-NIC from Santa Cruz Biotechnology
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GFRα-4 Double Nickase Plasmid (h2) - sc-408595-NIC-2 from Santa Cruz Biotechnology
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GFRα-4 CRISPR Activation Plasmid (h) - sc-408595-ACT from Santa Cruz Biotechnology
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GFRα-4 CRISPR Activation Plasmid (h2) - sc-408595-ACT-2 from Santa Cruz Biotechnology
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GFRα-4 Lentiviral Activation Particles (h) - sc-408595-LAC from Santa Cruz Biotechnology
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GFRα-4 Lentiviral Activation Particles (h2) - sc-408595-LAC-2 from Santa Cruz Biotechnology
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GFR-α4 siRNA (h) - sc-60683 from Santa Cruz Biotechnology
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GFR-α4 shRNA Plasmid (h) - sc-60683-SH from Santa Cruz Biotechnology
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GFR-α4 shRNA (h) Lentiviral Particles - sc-60683-V from Santa Cruz Biotechnology
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GFR alpha-4/GDNF R alpha-4/Persephin receptor RNAi - H00064096-R04 from Novus Biologicals
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GFR alpha-4/GDNF R alpha-4/Persephin receptor RNAi - H00064096-R06 from Novus Biologicals
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GFR alpha-4/GDNF R alpha-4/Persephin receptor RNAi - H00064096-R05 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9250 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9250 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05600 from Sigma-Aldrich
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GFRA4 siRNA (Human) - CRJ1916 from Cohesion Biosciences
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GFRA4 - MBS8201578 from MyBioSource
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shRNA set against Human Gfra4 (NM_022139.3) - SHH300710 from Creative biogene
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shRNA set against Human GFRA4(NM_022139.3) - SHH082775 from Creative biogene
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shRNA set against Human GFRA4(NM_145762.2) - SHH082811 from Creative biogene
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GFRA4 shRNA Plasmid (Human) - CHJ1916 from Cohesion Biosciences
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GFRA4 miRNA 3'UTR clone - MiUTR1H-04018 from Creative biogene
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GFRA4 miRNA 3'UTR clone - MiUTR1H-04019 from Creative biogene
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