HLCS

Gene Symbol	HLCS
Entrez Gene	3141
Alt Symbol	HCS
Species	Human
Gene Type	protein-coding
Description	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Other Description	biotin apo-protein ligase|biotin--[acetyl-CoA-carboxylase] ligase|biotin--[methylcrotonoyl-CoA-carboxylase] ligase|biotin--[methylmalonyl-CoA-carboxytransferase] ligase|biotin--protein ligase|holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
Swissprots	B2RAH1 D3DSG6 P50747 Q99451
Accessions	BAA89434 BAA95510 BAA95511 BAB68550 EAX09731 EAX09732 P50747 AJ001864 CAA05056 AK307940 AK314189 BAG36868 BC060787 AAH60787 BI094308 BQ775124 CB049233 D23672 BAA04902 D87328 BAA13332 DA334377 DB290499 H17102 X80160 XM_005260953 XP_005261010 XM_005260954 XP_005261011 XM_005260955 XP_005261012 XM_005260956 XP_005261013 XM_006723994 XP_006724057 XM_006723995 XP_006724058 XM_011529538 XP_011527840 XM_011529539 XP_011527841 XM_011529540 XP_011527842 XM_011529541 XP_011527843 XM_011529542 XP_011527844 NM_000411 NP_000402 NM_001242784 NP_001229713 NM_001242785 NP_001229714
Function	Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.
Subcellular Location	Cytoplasm. Mitochondrion.
Tissue Specificity	Mostly expressed in muscle, placenta, in lesser extent in the brain, kidney, pancreas, liver and lung.
Top Pathways	Biotin metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HLCS-Over-expression-Lysate - LY15598a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

HLCS 293T Cell Transient Overexpression Lysate(Denatured) - H00003141-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HLCS overexpression lysate - LY400145 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

HLCS 293 Cell Lysate - 400226 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

HLCS Overexpression Lysate (Denatured) - H00003141-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

HLCS Overexpression Lysate (Native) - NBL1-11597 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

HLCS Over-expression Lysate Product - GWB-6170B7 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human HLCS Knockdown Stable Cell Line - CSC-DC007105 from Creative biogene Category Cell Line Species Human

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